Evidence map›Paper›PMID 35831010›Full record

SynthesisEuropean respiratory review : an official journal of the European Respiratory Society2022

Impact of pulmonary embolism response teams on acute pulmonary embolism: a systematic review and meta-analysis.

Derlis Fleitas Sosa, Andrew L Lehr, Huaqing Zhao, Stephanie Roth, Vlad Lakhther, Riyaz Bashir, Gary Cohen, Joseph Panaro, Thomas S Maldonado, James Horowitz and 4 more

Open access · diamondAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in European respiratory review : an official journal of the European Respiratory Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
10.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 54 citations in OpenAlex.

  1. Article
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  18. A multidisciplinary pulmonary embolism response team (PERT): first experience from a single center in Germany.Clinical research in cardiology : official journal of the German Cardiac Society · 2024
    Article
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Derlis Fleitas SosaDept of Thoracic Medicine and Surgery, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, USA christianderlis@gmail.com.ORCID https://orcid.org/0000-0001-7648-5276
Andrew L LehrDivision of Pulmonary, Critical Care and Sleep Medicine, New York University Langone Health, New York, NY, USA.
Huaqing ZhaoDept of Clinical Sciences, Temple University School of Medicine, Philadelphia, PA, USA.
Stephanie RothBiomedical and Research Services Librarian, Simmy and Harry Ginsburg Library, Temple University, Philadelphia, PA, USA.ORCID https://orcid.org/0000-0001-5415-1718
Vlad LakhtherDept of Cardiovascular Diseases, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, USA.
Riyaz BashirDept of Cardiovascular Diseases, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, USA.
Gary CohenDept of Radiology, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, USA.
Joseph PanaroDept of Radiology, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, USA.
Thomas S MaldonadoDivision of Vascular Surgery, New York University Langone Health, New York, NY, USA.
James HorowitzDivision of Cardiology, New York University Langone Health, New York, NY, USA.
Nancy E AmorosoDivision of Pulmonary, Critical Care and Sleep Medicine, New York University Langone Health, New York, NY, USA.
Gerard J CrinerDept of Thoracic Medicine and Surgery, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, USA.
Shari B BrosnahanDivision of Pulmonary, Critical Care and Sleep Medicine, New York University Langone Health, New York, NY, USA.ORCID https://orcid.org/0000-0002-2092-3633
Parth RaliDept of Thoracic Medicine and Surgery, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, USA.ORCID https://orcid.org/0000-0002-2432-8137
Temple University · USNYU Langone Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe impact of pulmonary embolism response teams (PERTs) on treatment choice and outcomes of patients with acute pulmonary embolism (PE) is still uncertain.

objectiveTo determine the effect of PERTs in the management and outcomes of patients with PE.

methodsPubMed, Embase, Web of Science, CINAHL, WorldWideScience and MedRxiv were searched for original articles reporting PERT patient outcomes from 2009. Data were analysed using a random effects model.

results16 studies comprising 3827 PERT patients and 3967 controls met inclusion criteria. The PERT group had more patients with intermediate and high-risk PE (66.2%) compared to the control group (48.5%). Meta-analysis demonstrated an increased risk of catheter-directed interventions, systemic thrombolysis and surgical embolectomy (odds ratio (OR) 2.10, 95% confidence interval (CI) 1.74-2.53; p<0.01), similar bleeding complications (OR 1.10, 95% CI 0.88-1.37) and decreased utilisation of inferior vena cava (IVC) filters (OR 0.71, 95% CI 0.58-0.88; p<0.01) in the PERT group. Furthermore, there was a nonsignificant trend towards decreased mortality (OR 0.87, 95% CI 0.71-1.07; p=0.19) with PERTs.

conclusionsThe PERT group showed an increased use of advanced therapies and a decreased utilisation of IVC filters. This was not associated with increased bleeding. Despite comprising more severe PE patients, there was a trend towards lower mortality in the PERT group.

Indexed as

Pulmonary EmbolismVena Cava FiltersAcute DiseaseEmbolectomyHemorrhageHumans

Identifiers

PMID35831010
PMCPMC9724819
OpenAlexW4285094387

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.