Evidence map›Paper›PMID 35830826›Full record

ArticleImmunity2022

Epithelial STAT6 O-GlcNAcylation drives a concerted anti-helminth alarmin response dependent on tuft cell hyperplasia and Gasdermin C.

Ming Zhao, Kaiqun Ren, Xiwen Xiong, Yue Xin, Yujie Zou, Jason C Maynard, Angela Kim, Alexander P Battist, Navya Koneripalli, Yusu Wang and 19 more

Abstract readPublished Erratum
In one paragraph

Article in Immunity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Review
  10. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

29 authors.

Ming Zhao
Kaiqun Ren
Xiwen Xiong
Yue Xin
Yujie Zou
Jason C Maynard
Angela Kim
Alexander P Battist
Navya Koneripalli
Yusu Wang
Qianyue Chen
Ruyue Xin
Chenyan Yang
Rong Huang
Jiahui Yu
Zan Huang
Zengdi Zhang
Haiguang Wang
Daoyuan Wang
Yihui Xiao
Oscar C Salgado
Nicholas N Jarjour
Kristin A Hogquist
Xavier S Revelo
Alma L Burlingame
Xiang Gao
Jakob von Moltke
Zhaoyu Lin
Hai-Bin Ruan

Funding

Tuft cell effector functions in the small intestineR01AI145848 · NIAID · UNIVERSITY OF WASHINGTON · PI VON MOLTKE, JAKOB H. · 2020 to 2024
$2.8M
Sensing of helminths by tuft cellsDP2AI136596 · NIAID · UNIVERSITY OF WASHINGTON · PI VON MOLTKE, JAKOB H. · 2017 to 2017
$2.6M
Intestinal O-GlcNAc signaling and mucosal host defenseR01AI162791 · NIAID · UNIVERSITY OF MINNESOTA · PI Hai-Bin Ruan · 2022 to 2026
$2.4M
Protein O-GlcNAcylation in Regulatory T Cell FunctionR01AI139420 · NIAID · UNIVERSITY OF MINNESOTA · PI RUAN, HAI-BIN · 2019 to 2023
$2.3M
Tuft Cell Effector Functions in the IntestineR37AI145848 · NIAID · UNIVERSITY OF WASHINGTON · PI Jakob H. von Moltke · 2025 to 2026
$1.4M
Intestinal O-GlcNAc signaling and mucosal host defenseR56AI162791 · NIAID · UNIVERSITY OF MINNESOTA · PI RUAN, HAI-BIN · 2021 to 2021
$484k
O-GlcNAc signaling enables the intestinal epithelial remodeling associated with type 2 immunityR21AI140109 · NIAID · UNIVERSITY OF MINNESOTA · PI RUAN, HAI-BIN · 2018 to 2019
$424k
NIAID NIH HHS DP2 AI136596NIAID NIH HHS R01 AI139420NIAID NIH HHS R01 AI162791NIAID NIH HHS R21 AI140109NIAID NIH HHS R37 AI145848NIAID NIH HHS R56 AI162791
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID35830826
PMCPMC9336012

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.