Evidence map›Paper›PMID 35830612›Full record

ArticleJournal of neurophysiology2022

Laryngeal and swallow dysregulation following acute cervical spinal cord injury.

Teresa Pitts, Kimberly E Iceman, Alyssa Huff, M Nicholas Musselwhite, Michael L Frazure, Kellyanna C Young, Clinton L Greene, Dena R Howland

Open access · greenAbstract read
In one paragraph

Article in Journal of neurophysiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
5.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Observational
  5. Article
  6. An update on spinal cord injury and diaphragm neuromotor control.Expert review of respiratory medicine · 2025
    Review
  7. Effects of baclofen on swallow motor pattern.Frontiers in neurology · 2025
    Article
  8. Article
  9. Serotonin therapies for opioid-induced disordered swallow and respiratory depression.Journal of applied physiology (Bethesda, Md. : 1985) · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Deglutition and the Regulation of the Swallow Motor Pattern.Physiology (Bethesda, Md.) · 2023 · on this map
    Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Teresa PittsKentucky Spinal Cord Injury Research Center, Department of Neurological Surgery, University of Louisville, Louisville, Kentucky.ORCID 0000-0001-9448-2175
Kimberly E IcemanKentucky Spinal Cord Injury Research Center, Department of Neurological Surgery, University of Louisville, Louisville, Kentucky.
Alyssa HuffCenter for Integrative Brain Research, Seattle Children's Research Institute, Seattle, Washington.ORCID 0000-0003-2817-251X
M Nicholas MusselwhiteKentucky Spinal Cord Injury Research Center, Department of Neurological Surgery, University of Louisville, Louisville, Kentucky.
Michael L FrazureKentucky Spinal Cord Injury Research Center, Department of Neurological Surgery, University of Louisville, Louisville, Kentucky.ORCID 0000-0002-8775-7692
Kellyanna C YoungKentucky Spinal Cord Injury Research Center, Department of Neurological Surgery, University of Louisville, Louisville, Kentucky.
Clinton L GreeneKentucky Spinal Cord Injury Research Center, Department of Neurological Surgery, University of Louisville, Louisville, Kentucky.ORCID 0000-0002-2448-9360
Dena R HowlandKentucky Spinal Cord Injury Research Center, Department of Neurological Surgery, University of Louisville, Louisville, Kentucky.ORCID 0000-0001-7277-2550
University of Louisville · US

Funding

Functional mapping of peripheral and central circuits for airway protection and breathingOT2OD023854 · OD · UNIVERSITY OF FLORIDA · PI BOLSER, DONALD C · 2016 to 2020
$10.8M
Central and Peripheral Regulation of Laryngeal AdductionR01HL163008 · NHLBI · UNIVERSITY OF FLORIDA · PI BOLSER, DONALD C, PITTS, TERESA G · 2022 to 2025
$2.8M
Influence of Opioids on the Brainstem Respiratory NetworkR01HL155721 · NHLBI · UNIVERSITY OF FLORIDA · PI BOLSER, DONALD C, MORRIS, KENDALL FRANCIS · 2021 to 2024
$2.7M
Central Mechanisms of Airway ProtectionR01HL103415 · NHLBI · UNIVERSITY OF FLORIDA · PI BOLSER, DONALD C, DAVENPORT, PAUL W · 2010 to 2013
$2.2M
Regulation of swallow and the effects of high cervical spinal cord injuryR01NS110169 · NINDS · UNIVERSITY OF LOUISVILLE · PI PITTS, TERESA G · 2019 to 2023
$1.7M
NHLBI NIH HHS R01 HL103415NHLBI NIH HHS R01 HL155721NHLBI NIH HHS R01 HL163008NIH HHS OT2 OD023854NINDS NIH HHS R01 NS110169
6 · The paper itself

Abstract

Laryngeal function is vital to airway protection. Although swallow is mediated by the brainstem, the mechanism underlying the increased risk of dysphagia after cervical spinal cord injury (SCI) is unknown. We hypothesized that:

Indexed as

Cervical CordDeglutition DisordersSpinal Cord InjuriesAnimalsDiaphragmPhrenic NerveRatsRats, Sprague-DawleySpinal Cordbreathingcervicallarynxspinal cord injuryswallow

Identifiers

PMID35830612
PMCPMC9359645
OpenAlexW4285087540

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.