Evidence map›Paper›PMID 35830303›Full record

ArticlePaediatric and perinatal epidemiology2023

Exposure to the early COVID-19 pandemic and early, moderate and overall preterm births in the United States: A conception cohort approach.

Claire E Margerison, Tim A Bruckner, Colleen MacCallum-Bridges, Ralph Catalano, Joan A Casey, Alison Gemmill

Open access · greenAbstract read
In one paragraph

Article in Paediatric and perinatal epidemiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
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  6. Selection in utero against male twins in the United States early in the COVID-19 pandemic.American journal of human biology : the official journal of the Human Biology Council · 2023
    Article
  7. Article
  8. Article
  9. A novel indicator of selectionEvolution, medicine, and public health · 2023
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Claire E MargerisonDepartment of Epidemiology and Biostatistics, Michigan State University, East Lansing, Michigan, USA.ORCID 0000-0003-0692-2252
Tim A BrucknerDepartment of Health, Society, and Behavior, Center for Population, Inequality, and Policy, University of California, Irvine, California, USA.ORCID 0000-0002-6927-964X
Colleen MacCallum-BridgesDepartment of Epidemiology and Biostatistics, Michigan State University, East Lansing, Michigan, USA.
Ralph CatalanoSchool of Public Health, University of California, Berkeley, California, USA.ORCID 0000-0001-7240-415X
Joan A CaseyDepartment of Environmental Health Sciences, Columbia Mailman School of Public Health, New York, New York, USA.
Alison GemmillDepartment of Population, Family and Reproductive Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.ORCID 0000-0001-5879-9730
Michigan State University · USColumbia University · USJohns Hopkins University · USUniversity of California, Berkeley · USUniversity of California, Irvine · US

Funding

Racial disparities in preterm births and fetal lossesR01HD103736 · NICHD · UNIVERSITY OF CALIFORNIA-IRVINE · PI BRUCKNER, TIM ALLEN · 2021 to 2025
$2.7M
NICHD NIH HHS R01 HD103736
6 · The paper itself

Abstract

backgroundThe United States (US) data suggest fewer-than-expected preterm births in 2020, but no study has examined the impact of exposure to the early COVID-19 pandemic at different points in gestation on preterm birth.

objectiveOur objective was to determine-among cohorts exposed to the early COVID-19 pandemic-whether observed counts of overall, early and moderately preterm birth fell outside the expected range.

methodsWe used de-identified, cross-sectional, national birth certificate data from 2014 to 2020. We used month and year of birth and gestational age to estimate month of conception for birth. We calculated the count of overall (<37 weeks gestation), early (<33 weeks gestation) and moderately (33 to <37 weeks gestation) preterm birth by month of conception. We employed time series methods to estimate expected counts of preterm birth for exposed conception cohorts and identified cohorts for whom the observed counts of preterm birth fell outside the 95% detection interval of the expected value.

resultsAmong the 23,731,146 births in our study, the mean prevalence of preterm birth among monthly conception cohorts was 9.7 per 100 live births. Gestations conceived in July, August or December of 2019-that is exposed to the early COVID-19 pandemic in the first or third trimester-yielded approximately 3245 fewer moderately preterm and 3627 fewer overall preterm births than the expected values for moderate and overall preterm. Gestations conceived in August and October of 2019-that is exposed to the early COVID-19 pandemic in the late second to third trimester-produced approximately 498 fewer early preterm births than the expected count for early preterm.

conclusionsExposure to the early COVID-19 pandemic may have promoted longer gestation among close-to-term pregnancies, reduced risk of later preterm delivery among gestations exposed in the first trimester or induced selective loss of gestations.

Indexed as

COVID-19Premature BirthCross-Sectional StudiesFemaleHumansInfant, NewbornLive BirthPandemicsPregnancyUnited StatesCOVID-19 pandemicpregnancypremature birthtime series

Identifiers

PMID35830303
PMCPMC9350314
OpenAlexW4285088366

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.