ArticleInternational journal of cancer2022
Diet-wide association study of 92 foods and nutrients and lung cancer risk in the European Prospective Investigation into Cancer and Nutrition study and the Netherlands Cohort Study.
Article in International journal of cancer, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.
- The association between dietary fiber intake and risk of lung cancer: a GRADE-assessed systematic review and dose response meta-analysis of prospective cohort studies.Nutrition journal · 2026Pooled it
- Sugar sweetened and artificially sweetened beverages, fruit and vegetable juices and cancer risk: a World Cancer Research Fund International Global Cancer Update Programme (CUP Global) systematic literature review and meta-analysis.medRxiv : the preprint server for health sciences · 2026Article
- Analysis and prediction of the burden of lung cancer attributable to diet low in fruits in China and the global from 1990 to 2021.PloS one · 2026Article
- WCRF/AICR dietary adherence-associated metabolic bridge phenotypes and incident lung cancer risk: a prospective cohort study of the UK Biobank.Frontiers in nutrition · 2026Article
- Higher carbohydrate quality, but not quantity, is associated with lower lung cancer risk in a population-based prospective cohort study.Frontiers in nutrition · 2026Article
- Association between new dietary index for gut microbiota and lung cancer: A population-based study.Medicine · 2025Article
- Article
- Historical data analysis and future prediction of lung cancer in Zhejiang province, China.Scientific reports · 2025Article
- Fruit and Vegetable Intake in Relation to Lung Cancer Risk: A Systematic Review and Dose-response Meta-analysis of Prospective Cohort Studies.Journal of cancer prevention · 2025Review
- Lung Cancer incidence in both sexes across global areas: data from 1978 to 2017 and predictions up to 2035.BMC pulmonary medicine · 2025Article
- Global burden and trends analysis of common cancers attributable to dietary risks from 1990 to 2021 and projection to 2050: a secondary analysis for the global burden of disease study 2021.Frontiers in nutrition · 2025Article
- Association between fruit intake and non-small cell lung cancer: a Mendelian randomization study.Translational lung cancer research · 2024Article
- Adherence to the low-fat diet pattern reduces the risk of lung cancer in American adults aged 55 years and above: a prospective cohort study.The journal of nutrition, health & aging · 2024Article
- A diet-wide association study for liver cancer risk: findings from a prospective cohort study in Chinese men.European journal of epidemiology · 2024Article
- A diet-wide association study for liver cancer risk: findings from a prospective cohort study in Chinese women.Journal of nutritional science · 2024Article
- Association between adherence to Eat-Lancet diet and incidence and mortality of lung cancer: A prospective cohort study.Cancer science · 2023Article
- The Modulatory Effects of Fatty Acids on Cancer Progression.Biomedicines · 2023Review
- Associations between diet and incidence risk of lung cancer: A Mendelian randomization study.Frontiers in nutrition · 2023Article
- Diet-wide association study of 92 foods and nutrients and lung cancer risk in the European Prospective Investigation into Cancer and Nutrition study and the Netherlands Cohort Study.International journal of cancer · 2022Article
Corrections and comments
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Authors and funding
36 authors at 20 institutions in 12 countries.
Funding
Abstract
It is unclear whether diet, and in particular certain foods or nutrients, are associated with lung cancer risk. We assessed associations of 92 dietary factors with lung cancer risk in 327 790 participants in the European Prospective Investigation into Cancer and Nutrition (EPIC). Cox regression yielded adjusted hazard ratios (HRs) and 95% confidence intervals (CIs) per SD higher intake/day of each food/nutrient. Correction for multiple comparisons was performed using the false discovery rate and identified associations were evaluated in the Netherlands Cohort Study (NLCS). In EPIC, 2420 incident lung cancer cases were identified during a median of 15 years of follow-up. Higher intakes of fibre (HR per 1 SD higher intake/day = 0.91, 95% CI 0.87-0.96), fruit (HR = 0.91, 95% CI 0.86-0.96) and vitamin C (HR = 0.91, 95% CI 0.86-0.96) were associated with a lower risk of lung cancer, whereas offal (HR = 1.08, 95% CI 1.03-1.14), retinol (HR = 1.06, 95% CI 1.03-1.10) and beer/cider (HR = 1.04, 95% CI 1.02-1.07) intakes were positively associated with lung cancer risk. Associations did not differ by sex and there was less evidence for associations among never smokers. None of the six associations with overall lung cancer risk identified in EPIC were replicated in the NLCS (2861 cases), however in analyses of histological subtypes, inverse associations of fruit and vitamin C with squamous cell carcinoma were replicated in the NLCS. Overall, there is little evidence that intakes of specific foods and nutrients play a major role in primary lung cancer risk, but fruit and vitamin C intakes seem to be inversely associated with squamous cell lung cancer.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.