Evidence map›Paper›PMID 35829895›Full record

ArticleInternational journal of hematology2022

Renal involvement of lymphomas proven by kidney biopsy: report of 10 cases from a tertiary care center and comparison with the literature.

Fanny Urbain, Sophie Ferlicot, Laurence Rocher, Florent L Besson, Léa Gomez, Jean-Marie Michot, Thierry Lazure, Xavier Mariette, Gaëtane Nocturne, Olivier Lambotte and 2 more

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in International journal of hematology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Primary renal lymphoma in a uremic patient.Oxford medical case reports · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Fanny UrbainAssistance Publique-Hôpitaux de Paris, Service de Médecine Interne et Immunologie Clinique, Groupe Hospitalier Universitaire Paris-Saclay, Hôpital Bicêtre, CHU de Bicêtre, 78, rue du Général Leclerc, 94275, Le Kremlin-Bicêtre cedex, France.
Sophie FerlicotAssistance Publique-Hôpitaux de Paris, Service d'Anatomie et Cytologie Pathologique, Groupe Hospitalier Universitaire Paris-Saclay, Hôpital Bicêtre, 94275, Le Kremlin-Bicêtre cedex, France.
Laurence RocherAssistance Publique-Hôpitaux de Paris, Service de Radiologie, Groupe Hospitalier Universitaire Paris-Saclay, Hôpital Béclère, Clamart, France.
Florent L BessonAssistance Publique-Hôpitaux de Paris, Service de Biophysique et Médecine Nucléaire-Imagerie Moléculaire, Groupe Hospitalier Universitaire Paris-Saclay, Hôpital Bicêtre, 94275, Le Kremlin-Bicêtre cedex, France.
Léa GomezAssistance Publique-Hôpitaux de Paris, Service de Biophysique et Médecine Nucléaire-Imagerie Moléculaire, Groupe Hospitalier Universitaire Paris-Saclay, Hôpital Bicêtre, 94275, Le Kremlin-Bicêtre cedex, France.
Jean-Marie MichotDépartement d'Innovation Thérapeutique et d'Essais Précoces (DITEP), Institut, Gustave Roussy, Villejuif, France.
Thierry LazureAssistance Publique-Hôpitaux de Paris, Service d'Anatomie et Cytologie Pathologique, Groupe Hospitalier Universitaire Paris-Saclay, Hôpital Bicêtre, 94275, Le Kremlin-Bicêtre cedex, France.
Xavier MarietteINSERM UMR 1184, Immunologie des Maladies Virales et Autoimmunes (IMVA), Université Paris-Saclay, 94275, Le Kremlin-Bicêtre cedex, France.
Gaëtane NocturneINSERM UMR 1184, Immunologie des Maladies Virales et Autoimmunes (IMVA), Université Paris-Saclay, 94275, Le Kremlin-Bicêtre cedex, France.
Olivier LambotteAssistance Publique-Hôpitaux de Paris, Service de Médecine Interne et Immunologie Clinique, Groupe Hospitalier Universitaire Paris-Saclay, Hôpital Bicêtre, CHU de Bicêtre, 78, rue du Général Leclerc, 94275, Le Kremlin-Bicêtre cedex, France.
Mohamad ZaidanAssistance Publique-Hôpitaux de Paris, Service de Néphrologie, Groupe Hospitalier Universitaire Paris-Saclay, Hôpital Bicêtre, 94275, Le Kremlin-Bicêtre cedex, France.
Nicolas NoelAssistance Publique-Hôpitaux de Paris, Service de Médecine Interne et Immunologie Clinique, Groupe Hospitalier Universitaire Paris-Saclay, Hôpital Bicêtre, CHU de Bicêtre, 78, rue du Général Leclerc, 94275, Le Kremlin-Bicêtre cedex, France. nicolas.noel@aphp.fr.ORCID http://orcid.org/0000-0003-4055-617X
Inserm · FRAssistance Publique – Hôpitaux de Paris · FRCentre National de la Recherche Scientifique · FRUniversité Paris-Saclay · FRInstitut Gustave Roussy · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lymphomas localized in the kidney are a rare entity that may be challenging to diagnose. We analyzed data from 10 patients with renal involvement of lymphoma diagnosed between 2009 and 2019 on fine needle biopsy from our tertiary center, and compared these with findings of 160 cases reported in the literature. Diffuse large B-cell lymphoma was the main histology subtype (40 and 38% in our sample and in the literature, respectively), followed by low-grade B-cell lymphomas, mostly from the marginal zone (MZ). Altogether, 106 patients had urological inaugural symptoms and 64 had general symptoms. Patients with urological presentation more often had renal masses than diffuse infiltration (p < 0.001), unilateral tumors (p = 0.0036) and low-grade B-cell lymphomas (17 vs 6%, p = 0.043). In both groups, nearly one-fourth of patients had diffuse (stage IV) lymphomas. Overall survival did not differ by the presence of urological/systemic symptoms, stage or aggressive lymphoma status. Notably, 3 of 10 patients from our series had MZ lymphomas associated with primary Sjögren syndrome revealed by acute kidney injury, including one where the autoimmune disease was detected. Lymphoproliferative disorders localized in the kidney are a challenging condition that can lead to detection of aggressive or diffuse lymphomas.

Indexed as

Lymphoma, B-Cell, Marginal ZoneLymphoma, Large B-Cell, DiffuseBiopsyHumansKidneyTertiary Care CentersLymphoproliferative disordersPrimary Sjögren’s syndromeRenal lymphomaRenal tumor

Identifiers

PMID35829895
OpenAlexW4285087572

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.