Evidence map›Paper›PMID 35829750›Full record

ArticleClinical research in cardiology : official journal of the German Cardiac Society2023

Association of changes in cardiovascular health levels with incident cardiovascular events and mortality in patients with atrial fibrillation.

Seunghoon Cho, Pil-Sung Yang, Daehoon Kim, Seng Chan You, Jung-Hoon Sung, Eunsun Jang, Hee Tae Yu, Tae-Hoon Kim, Hui-Nam Pak, Moon-Hyoung Lee and 1 more

Abstract read
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In one paragraph

Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Seunghoon Cho *Division of Cardiology, Department of Internal Medicine, Severance Hospital, Yonsei University, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, Republic of Korea.
Pil-Sung Yang *Department of Cardiology, CHA Bundang Medical Center, CHA University, Seongnam, Republic of Korea.
Daehoon KimDivision of Cardiology, Department of Internal Medicine, Severance Hospital, Yonsei University, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, Republic of Korea.
Seng Chan YouDepartment of Biomedical Informatics, Yonsei University, Seoul, Republic of Korea.
Jung-Hoon SungDepartment of Cardiology, CHA Bundang Medical Center, CHA University, Seongnam, Republic of Korea.
Eunsun JangDivision of Cardiology, Department of Internal Medicine, Severance Hospital, Yonsei University, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, Republic of Korea.
Hee Tae YuDivision of Cardiology, Department of Internal Medicine, Severance Hospital, Yonsei University, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, Republic of Korea.
Tae-Hoon KimDivision of Cardiology, Department of Internal Medicine, Severance Hospital, Yonsei University, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, Republic of Korea.
Hui-Nam PakDivision of Cardiology, Department of Internal Medicine, Severance Hospital, Yonsei University, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, Republic of Korea.
Moon-Hyoung LeeDivision of Cardiology, Department of Internal Medicine, Severance Hospital, Yonsei University, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, Republic of Korea.
Boyoung JoungDivision of Cardiology, Department of Internal Medicine, Severance Hospital, Yonsei University, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, Republic of Korea. cby6908@yuhs.ac.ORCID http://orcid.org/0000-0001-9036-7225
Yonsei University · KRCHA University Bundang Medical Center · KR

Funding

Ministry of Health and Welfare HC19C0130
6 · The paper itself

Abstract

backgroundRisk factor management is crucial in the management of atrial fibrillation (AF). We investigated the association of changes in cardiovascular health (CVH) levels after AF diagnosis with incident cardiovascular events and mortality.

methodsFrom the Korea National Health Insurance Service database, 76,628 patients newly diagnosed with AF (2005-2015) with information on health examinations before and after AF diagnosis were assessed. According to the change in the 12-point CVH score before and after AF diagnosis, patients were stratified into four groups: consistently low (score 0-7 to 0-7), high-to-low (8-12 to 0-7), low-to-high (0-7 to 8-12), and consistently high (8-12 to 8-12) CVH levels. Risks of cardiovascular events and death were analyzed using weighted Cox regression models with inverse probability of treatment weighting (IPTW) for balance across study groups.

resultsThe mean age of study participants was 58.3 years, 50,285 were men (63.1%), and the mean follow-up was 5.5 years. After IPTW, low-to-high (hazard ratio [95% confidence interval], 0.83 [0.76-0.92]) and consistently high (0.80 [0.74-0.87]) CVH levels were associated with a lower risk of ischemic stroke than consistently low CVH. Low-to-high (0.66 [0.52-0.84]) and consistently high (0.52 [0.42-0.64]) CVH levels were associated with a lower risk of acute myocardial infarction. Maintaining high CVH was associated with reduced risks of heart failure hospitalization (0.85 [0.75-0.95]) and all-cause death (0.82 [0.77-0.88]), respectively, compared with consistently low CVH.

conclusionsImproving CVH levels and maintaining high CVH levels after AF diagnosis is associated with lower risks of subsequent cardiovascular events and mortality.

Indexed as

Atrial FibrillationCardiovascular DiseasesHeart FailureMyocardial InfarctionFemaleHealth StatusHumansMaleMiddle AgedRisk FactorsAtrial fibrillationCardiovascular diseaseCardiovascular healthCardiovascular risk factorsMortality

Identifiers

PMID35829750
OpenAlexW4285086416

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.