Evidence map›Paper›PMID 35829695›Full record

ArticleeLife2022

A CD4

Massimo Andreatta, Ariel Tjitropranoto, Zachary Sherman, Michael C Kelly, Thomas Ciucci, Santiago J Carmona

Open access · goldAbstract read
In one paragraph

Article in eLife, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
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  10. Review
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  15. Advances in Single-Cell Sequencing for Infectious Diseases: Progress and Perspectives.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Massimo AndreattaDepartment of Oncology, UNIL CHUV and Ludwig Institute for Cancer Research Lausanne, University of Lausanne, Lausanne, Switzerland.ORCID 0000-0002-8036-2647
Ariel TjitropranotoDavid H. Smith Center for Vaccine Biology and Immunology, Department of Microbiology and Immunology, University of Rochester, Rochester, United States.ORCID 0000-0001-5525-5236
Zachary ShermanDavid H. Smith Center for Vaccine Biology and Immunology, Department of Microbiology and Immunology, University of Rochester, Rochester, United States.
Michael C KellySingle Cell Analysis Facility, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research Inc, Frederick, United States.ORCID 0000-0003-0654-2778
Thomas Ciucci *David H. Smith Center for Vaccine Biology and Immunology, Department of Microbiology and Immunology, University of Rochester, Rochester, United States.ORCID 0000-0002-5828-0207
Santiago J Carmona *Department of Oncology, UNIL CHUV and Ludwig Institute for Cancer Research Lausanne, University of Lausanne, Lausanne, Switzerland.ORCID 0000-0002-2495-0671
SIB Swiss Institute of Bioinformatics · CHUniversity of Rochester · USLeidos (United States) · USNational Institutes of Health · US

Funding

CCR NIH HHS HHSN261200800001CNCI NIH HHS HHSN261200800001E
6 · The paper itself

Abstract

CD4

Indexed as

T-LymphocytesVirus DiseasesAnimalsCD4-Positive T-LymphocytesMiceReceptors, Antigen, T-CellReceptors, Antigen, T-CellCD4 T cellsexhaustiongene expressionimmunologyinflammationmousesingle-cell data sciencesingle-cell transcriptomicsviral infection

Identifiers

PMID35829695
PMCPMC9323004
OpenAlexW4285085644

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.