Evidence map›Paper›PMID 35822785›Full record

ArticleBiotech (Basel (Switzerland))2022

Characterisation of Omicron Variant during COVID-19 Pandemic and the Impact of Vaccination, Transmission Rate, Mortality, and Reinfection in South Africa, Germany, and Brazil.

Carolina Ribeiro Xavier, Rafael Sachetto Oliveira, Vinícius da Fonseca Vieira, Marcelo Lobosco, Rodrigo Weber Dos Santos

Abstract read
In one paragraph

Article in Biotech (Basel (Switzerland)), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Article
  2. Drivers of COVID-19 infections: Perspectives of managers in the Gauteng Department of Health, South Africa.South African family practice : official journal of the South African Academy of Family Practice/Primary Care · 2025
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  11. Extensive SARS-CoV-2 testing reveals BA.1/BA.2 asymptomatic rates and underreporting in school children.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2023
    Article
  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Carolina Ribeiro XavierDepartment of Computer Science, Federal University of São João del-Rei, São João del-Rei 36301-360, MG, Brazil.ORCID 0000-0002-2830-2217
Rafael Sachetto OliveiraDepartment of Computer Science, Federal University of São João del-Rei, São João del-Rei 36301-360, MG, Brazil.ORCID 0000-0003-0800-5984
Vinícius da Fonseca VieiraDepartment of Computer Science, Federal University of São João del-Rei, São João del-Rei 36301-360, MG, Brazil.ORCID 0000-0002-5051-3109
Marcelo LoboscoDepartment of Computer Science, Federal University of Juiz de Fora, Juiz de Fora 36036-330, MG, Brazil.ORCID 0000-0002-7205-9509
Rodrigo Weber Dos SantosDepartment of Computer Science, Federal University of Juiz de Fora, Juiz de Fora 36036-330, MG, Brazil.ORCID 0000-0002-0633-1391

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several variants of SARS-CoV-2 have been identified in different parts of the world, including Gamma, detected in Brazil, Delta, detected in India, and the recent Omicron variant, detected in South Africa. The emergence of a new variant is a cause of great concern. This work considers an extended version of an SIRD model capable of incorporating the effects of vaccination, time-dependent transmissibility rates, mortality, and even potential reinfections during the pandemic. We use this model to characterise the Omicron wave in Brazil, South Africa, and Germany. During Omicron, the transmissibility increased by five for Brazil and Germany and eight for South Africa, whereas the estimated mortality was reduced by three-fold. We estimated that the reported cases accounted for less than 25% of the actual cases during Omicron. The mortality among the nonvaccinated population in these countries is, on average, three to four times higher than the mortality among the fully vaccinated. Finally, we could only reproduce the observed dynamics after introducing a new parameter that accounts for the percentage of the population that can be reinfected. Reinfection was as high as 40% in South Africa, which has only 29% of its population fully vaccinated and as low as 13% in Brazil, which has over 70% and 80% of its population fully vaccinated and with at least one dose, respectively. The calibrated models were able to estimate essential features of the complex virus and vaccination dynamics and stand as valuable tools for quantifying the impact of protocols and decisions in different populations.

Indexed as

computational epidemiologyCOVID-19Omicron variantSIRDvaccination

Identifiers

PMID35822785
PMCPMC9264399

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.