ArticleCancer medicine2023
Global incidence, mortality and temporal trends of cancer in children: A joinpoint regression analysis.
Article in Cancer medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.
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Who cites it
32 citing papers in PubMed, 1 synthesis or guideline pooled it, 63 citations in OpenAlex.
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- Early-life infections and childhood cancer risk: a nationwide cohort study of 2 million children.BMC cancer · 2026Article
- Trends in Childhood and Adolescent Cancer Incidence Rates in the United States between 2001 and 2022.Cancer discovery · 2026Article
- LARS promotes osteosarcoma proliferation through leucine-dependent PRIM2 translation and DNA replication activation.Journal of experimental & clinical cancer research : CR · 2026Article
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- Internalized stigma among pediatric patients with osteosarcoma and retinoblastoma in Guatemala, Jordan, and Zimbabwe.Frontiers in oncology · 2026Article
- Nationwide trends in childhood cancer incidence and survival in Iran: analysis of national cancer registry data, 2005-2014.BMC pediatrics · 2025Article
- Leveraging diverse cell death patterns in osteosarcoma patients and identification of the function of FADS2 in osteosarcoma cells.Scientific reports · 2025Article
- The phosphatase CTDSPL2 promotes proliferation, invasion, metastasis and regorafenib resistance in osteosarcoma.Journal of bone oncology · 2025Article
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- Trend and Burden of Vitamin A Deficiency in 1990-2021 and Projection to 2050: A Systematic Analysis for the Global Burden of Disease Study 2021.Nutrients · 2025Article
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- Long-Term Oro-Dental Effects of Chemotherapy in a Pediatric Patient: A Case Study and a Proposed Oral Care Protocol.Journal of clinical medicine · 2025Article
- Epidemiology and clinical features of childhood malignant solid tumors in a single center in southwest China over 24 years.BMC pediatrics · 2025Article
- Factors affecting caregiver burden among parents of children with cancer: A path analysis.Journal of clinical nursing · 2025Article
- Chronic obstructive pulmonary disease burden attributable to tobacco and the trend change from 1990 to 2021 in China.Tobacco induced diseases · 2025Article
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Authors and funding
12 authors at 8 institutions in 7 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
methodsThe Cancer Incidence in Five Continents Time Trends, Nordic Cancer Registries, Surveillance, Epidemiology and End Results, WHO Mortality databases were assessed to extract the Age-Standardised Rates (ASR) of cancer incidence and mortality among children aged 0-14 years old. By using the ASRs, the country-specific Average Annual Percentage Change (AAPC) and its corresponding 95% confidence interval (CI) were calculated to determine the epidemiological cancer trend.
resultsIn 2020, the highest incidence of childhood cancer was found in countries with higher Human Development Index (HDI) (ASR = 15.7), yet the highest mortality was found in countries with lower HDIs (ASR = 4.8). As for incidence, seven countries had positive AAPC among boys; Slovakia (AAPC
conclusionsThe largest mortality and mortality to incidence ratio of childhood cancer were found in low-income countries. There was a substantial increasing trend of childhood cancer incidence, while overall its mortality has been decreasing over the past decade. More studies are needed to confirm the drivers behind these epidemiologic trends.
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