Evidence map›Paper›PMID 35822320›Full record

ArticleAmerican journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons2022

Organ transplantation using COVID-19-positive deceased donors.

Matthew J Bock, Gabrielle R Vaughn, Peter Chau, Jennifer A Berumen, John J Nigro, Elizabeth G Ingulli

Open access · greenAbstract read
In one paragraph

Article in American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. COVID-19 in organ donors: An organ procurement organization perspective.Transplant infectious disease : an official journal of the Transplantation Society · 2024
    Article
  5. Article
  6. Review
  7. Article
  8. Utilization of COVID-19 positive donors for Heart transplantation and associated short-term outcomes.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2023
    Article
  9. COVID-19: Has the Liver Been Spared?International journal of molecular sciences · 2023
    Review
  10. Review
  11. COVID-19 in donation and transplant.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2022
    Review
  12. Organ transplantation using COVID-19-positive deceased donors.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Matthew J BockDivision of Pediatric Cardiology, Department of Pediatrics, University of California at San Diego, San Diego, California, USA.ORCID 0000-0003-1357-4698
Gabrielle R VaughnDivision of Pediatric Cardiology, Department of Pediatrics, University of California at San Diego, San Diego, California, USA.
Peter ChauDivision of Pediatric Cardiology, Department of Pediatrics, University of California at San Diego, San Diego, California, USA.
Jennifer A BerumenDivision of Transplant and Hepatobiliary Surgery, Department of Surgery, University of California at San Diego, San Diego, California, USA.
John J NigroDivision of Pediatric Cardiovascular and Thoracic Surgery, Department of Surgery, University of California at San Diego, San Diego, California, USA.
Elizabeth G IngulliDivision of Pediatric Nephrology, Department of Pediatrics, University of California at San Diego, San Diego, California, USA.
University of California San Diego · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The COVID-19 pandemic has influenced organ transplantation decision making. Opinions regarding the utilization of coronavirus disease-2019 (COVID-19) donors are mixed. We hypothesize that COVID-19 infection of deceased solid organ transplant donors does not affect recipient survival. All deceased solid organ transplant donors with COVID-19 testing results from March 15, 2020 to September 30, 2021 were identified in the OPTN database. Donors were matched to recipients and stratified by the COVID-19 test result. Outcomes were assessed between groups. COVID-19 test results were available for 17 694 donors; 150 were positive. A total of 269 organs were transplanted from these donors, including 187 kidneys, 57 livers, 18 hearts, 5 kidney-pancreases, and 2 lungs. The median time from COVID-19 testing to organ recovery was 4 days for positive and 3 days for negative donors. Of these, there were 8 graft failures (3.0%) and 5 deaths (1.9%). Survival of patients receiving grafts from COVID-19-positive donors is equivalent to those receiving grafts from COVID-19-negative donors (30-day patient survival = 99.2% COVID-19 positive; 98.6% COVID-19 negative). Solid organ transplantation using deceased donors with positive COVID-19 results does not negatively affect early patient survival, though little information regarding donor COVID-19 organ involvement is known. While transplantation is feasible, more information regarding COVID-19-positive donor selection is needed.

Indexed as

COVID-19Organ TransplantationTissue and Organ ProcurementCOVID-19 TestingGraft SurvivalHumansPandemicsTissue Donorsclinical research/practicedonors and donation: deceasedinfection and infectious agents-viral: SARS-CoV-2/COVID-19infectious diseasepatient survivalsolid organ transplantationUnited Network for Organ Sharing (UNOS)

Identifiers

PMID35822320
PMCPMC9349433
OpenAlexW4285086986

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.