Evidence map›Paper›PMID 35822100›Full record

ArticleBrain communications2022

Structural integrity of the anterior mid-cingulate cortex contributes to resilience to delirium in SuperAging.

Yuta Katsumi, Bonnie Wong, Michele Cavallari, Tamara G Fong, David C Alsop, Joseph M Andreano, Nicole Carvalho, Michael Brickhouse, Richard Jones, Towia A Libermann and 9 more

Open access · goldAbstract read
In one paragraph

Article in Brain communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. The first 25 years of the Northwestern University SuperAging Program.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
  9. Review
  10. Article
  11. Article
  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 6 institutions in 1 country.

Yuta KatsumiHarvard Medical School, Boston MA, USA.ORCID https://orcid.org/0000-0003-0413-747X
Bonnie WongHarvard Medical School, Boston MA, USA.
Michele CavallariHarvard Medical School, Boston MA, USA.
Tamara G FongHarvard Medical School, Boston MA, USA.
David C AlsopHarvard Medical School, Boston MA, USA.
Joseph M AndreanoHarvard Medical School, Boston MA, USA.
Nicole CarvalhoFrontotemporal Disorders Unit, Massachusetts General Hospital, Boston MA, USA.
Michael BrickhouseFrontotemporal Disorders Unit, Massachusetts General Hospital, Boston MA, USA.
Richard JonesDepartment of Psychiatry and Human Behavior and Neurology, Brown University Warren Alpert Medical School, Providence RI, USA.ORCID https://orcid.org/0000-0002-1049-218X
Towia A LibermannHarvard Medical School, Boston MA, USA.
Edward R MarcantonioHarvard Medical School, Boston MA, USA.ORCID https://orcid.org/0000-0002-2911-4250
Eva SchmittHarvard Medical School, Boston MA, USA.
Mouhsin M ShafiHarvard Medical School, Boston MA, USA.
Alvaro Pascual-LeoneHarvard Medical School, Boston MA, USA.
Thomas TravisonHarvard Medical School, Boston MA, USA.ORCID https://orcid.org/0000-0002-1030-7175
Lisa Feldman BarrettHarvard Medical School, Boston MA, USA.
Sharon K InouyeHarvard Medical School, Boston MA, USA.
Bradford C DickersonHarvard Medical School, Boston MA, USA.
Alexandra TouroutoglouHarvard Medical School, Boston MA, USA.
Beth Israel Deaconess Medical Center · USHarvard University · USMassachusetts General Hospital · USBrigham and Women's Hospital · USBrown University · USNortheastern University · US

Funding

Research Education ComponentP30AG062421 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI Christine S Ritchie · 2019 to 2026
$36.5M
The Role of Inflammation in the Pathophysiology of Delirium and its Associated Long-Term Cognitive DeclineP01AG031720 · NIA · HEBREW REHABILITATION CENTER FOR AGED · PI SHAFI, MOUHSIN · 2010 to 2022
$26.7M
Advancing the Understanding of Postoperative Delirium Mechanisms via Multi-OmicsR01AG051658 · NIA · BETH ISRAEL DEACONESS MEDICAL CENTER · PI TOWIA A. LIBERMANN, EDWARD R MARCANTONIO · 2016 to 2026
$5.9M
NIDUS III: Advanced-Stage Development and Utilization of the NIDUS Research Infrastructure to Advance Interdisciplinary Aging Research inDeliriumR33AG071744 · NIA · JOHNS HOPKINS UNIVERSITY · PI John W. Devlin, Esther Seunghee Oh · 2021 to 2026
$4.7M
Mid-Career Mentoring Award for Patient-Oriented Research in AgingK24AG035075 · NIA · BETH ISRAEL DEACONESS MEDICAL CENTER · PI MARCANTONIO, EDWARD R · 2010 to 2021
$1.9M
TMS in Primary Progressive Aphasia: Modulation of Brain Networks and LanguageK23DC016912 · NIDCD · MASSACHUSETTS GENERAL HOSPITAL · PI TOUROUTOGLOU, ALEXANDRA · 2019 to 2023
$871k
NIA NIH HHS K24 AG035075NIA NIH HHS P01 AG031720NIA NIH HHS P30 AG062421NIA NIH HHS R01 AG051658NIA NIH HHS R33 AG071744NIDCD NIH HHS K23 DC016912
6 · The paper itself

Abstract

Despite its devastating clinical and societal impact, approaches to treat delirium in older adults remain elusive, making it important to identify factors that may confer resilience to this syndrome. Here, we investigated a cohort of 93 cognitively normal older patients undergoing elective surgery recruited as part of the Successful Aging after Elective Surgery study. Each participant was classified either as a SuperAger (

Indexed as

cortical thicknessMRIpostoperative deliriumsalience networksuccessful aging

Identifiers

PMID35822100
PMCPMC9272062
OpenAlexW4283656212

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.