Vitamin D assessment in patients with COVID-19 virus and correlation with severity.

Tarek M Yosef, Shereen A Saleh, Sara Fekry Ali, Ahmed Elmetwally Ahmed

Open access · diamondAbstract read

In one paragraph

Article in The Egyptian journal of internal medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

0.9field-weighted citation impact, top 27% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

Vitamin D Deficiency in Both Oral and Systemic Manifestations in SARS-CoV-2 Infection: Updated Review.Medicina (Kaunas, Lithuania) · 2022
Review

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Tarek M YosefGastroenterology, Hepatology and Internal Medicine Department, Ain Shams University, Cairo, Egypt.

Shereen A SalehGastroenterology, Hepatology and Internal Medicine Department, Ain Shams University, Cairo, Egypt.

Sara Fekry AliGastroenterology, Hepatology and Internal Medicine Department, Ain Shams University, Cairo, Egypt.

Ahmed Elmetwally AhmedGastroenterology, Hepatology and Internal Medicine Department, Ain Shams University, Cairo, Egypt.

Ain Shams University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Vitamin D may play a vital role in preventing the multi-system consequences of COVID-19 infections. The aim of this study is to evaluate the potential association between mean serum levels of vitamin D and COVID-19 and its correlation with severity and mortality. Results: A case-control study conducted on 80 Egyptian patients admitted at Ain Shams University designated hospitals, Cairo, Egypt, from March 2021 to September 2021. Regarding the laboratory investigations, we found that COVID-19 cases have significantly lower lymphocytic counts than controls. Regarding vitamin D, this study showed a statistically significant positive correlation between vitamin D and lymphocytes, and there were statistically significant negative correlations between vitamin D, neutrophil-lymphocyte ratio, C-reactive protein, blood urea nitrogen, serum creatinine, aspartate aminotransferase, alanine aminotransferase, ferritin, lactate dehydrogenase, and D-dimer. Conclusion: This study confirms that vitamin D deficiency is associated with the severity of COVID-19 clinically and laboratory.

Indexed as

COVID-19 virusNeutrophil-lymphocyte ratioVitamin D

Identifiers

PMID35822077

DOI10.1186/s43162-022-00142-8

PMCPMC9264737

OpenAlexW4284970165

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.