SynthesisThe Iowa orthopaedic journal2022
Operative Time and Risk of Surgical Site Infection and Periprosthetic Joint Infection: A Systematic Review and Meta-Analysis.
Synthesis in The Iowa orthopaedic journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
35 citing papers in PubMed.
- Injectable platelet-rich fibrin (iPRF) and postoperative outcomes in mandibular impacted third molar surgery: a split-mouth randomized controlled trial.BMC oral health · 2026Trial
- Postoperative outcomes of inguinal hernia repair performed by surgical residents in routine clinical practice: a retrospective single-center analysis.Innovative surgical sciences · 2026Article
- Capsular management in posterolateral total hip arthroplasty: impact on proprioception, balance, functional outcomes, and complications.Journal of orthopaedic surgery and research · 2026Article
- Microbiological Profile of Periprosthetic Infections Following Femoral Fracture: A Retrospective Analysis.Journal of clinical medicine · 2026Article
- Comparison of the learning curves of the osteotomy guide robot and guide plate-based robot-assisted total knee arthroplasty.Arthroplasty (London, England) · 2026Article
- Antimicrobial 3D printed implants for periprosthetic joint infections.Drug delivery and translational research · 2026Article
- Hook plate versus locking plate fixation in lateral clavicle fractures: operative efficiency and cumulative surgical burden in a propensity score-matched cohort study.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026Article
- Intraoperative vasopressor use as a risk factor for early periprosthetic joint infection after total joint arthroplasty: A retrospective cohort study.Journal of orthopaedics · 2026Article
- Effect of Caerin 1.9 Antimicrobial Peptide Gel on Early Bacterial Infections in Oral Titanium Implants: An Animal Study.International dental journal · 2026Article
- Determinants of Dehiscence and Wound Infections After Open Reduction and Internal Fixation of Femoral Shaft and Subtrochanteric fractures.Orthopedic reviews · 2026Article
- Synergistic integration of biomaterials in orthopedic implantation for infection preventing and tissue engineering.Regenerative biomaterials · 2026Review
- Geriatric Total Hip Arthroplasty: Fixation Strategies, Approaches and Outcomes.Journal of orthopaedics and sports medicine · 2026Article
- Automated Impaction Improves Femoral Component Canal Fit in Total Hip Arthroplasty: A Matched Study.Arthroplasty today · 2025Article
- Simple Intraoperative Method for Administration of Local Antibiotic Powder in Orthopaedic Surgery.Arthroscopy techniques · 2025Article
- Reduced periprosthetic fracture rate for a cemented anatomical versus a tapered polished stem in hip arthroplasty: A 6-year follow-up of a prospective observational cohort study.Journal of experimental orthopaedics · 2025Article
- Development and validation of a predictive nomogram for surgical site infection among general surgery patients in Amhara region Ethiopia.Scientific reports · 2025Article
- Incidence, predictors, and outcomes of sepsis in revision total hip arthroplasty (rTHA).Archives of orthopaedic and trauma surgery · 2025Observational
- Current trends of unicompartmental knee arthroplasty (UKA): choosing between robotic-assisted and conventional surgeries and timing of procedures.Arthroplasty (London, England) · 2025Article
- Cefazolin Alone Versus Cefazolin With Tobramycin or Gentamicin as Intraoperative Antibiotic Prophylaxis for Total Joint Arthroplasty.Arthroplasty today · 2025Article
- Standardized operating room nursing care is effective in preventing the occurrence of surgical wound infections.American journal of translational research · 2025Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The purpose of this study was to perform a systematic review and meta-analysis on the association between operative time and peri-prosthetic joint infection (PJI) after primary total hip arthroplasty (THA) and total knee arthroplasty (TKA). Methods: PubMed, Embase, and Cochrane CENTRAL databases were searched for relevant articles dating 2000-2020. Relationship of operative time and PJI rate in primary total joint arthroplasty (TJA) was evaluated by pooled odds ratios (OR) and 95% confidence intervals. Results: Six studies were identified for meta-analysis. TJA lasting greater than 120 minutes had greater odds of PJI (OR, 1.63 [1.00-2.66], p=0.048). Similarly, there were greater odds of PJI for TJA procedures lasting greater than 90 minutes (OR, 1.65 [1.27-2.14]; p<0.001). Separate analyses of TKA (OR, 2.01 [0.76-5.30]) and THA (OR, 1.06 [0.80-1.39]) demonstrated no difference in rates of PJI in cases of operative time ≥ 120 minutes versus cases < 120 minutes (p>0.05 for all). Using any surgical site infection (SSI) as an endpoint, both TJA (OR, 1.47 [1.181.83], p<0.001) and TKA (OR, 1.50 [1.08-2.08]; p=0.016) procedures lasting more versus less than 120 minutes demonstrated significantly higher odds of SSI. Conclusion: Following TJA, rates of SSI and PJI are significantly greater in procedures ≥120 minutes in duration relative to those < 120 minutes. When analyzing TKA separately, higher rates of SSI were observed in procedures ≥ 120 minutes in duration relative to those <120 minutes. Rates of PJI in TKA or THA procedures alone were not significantly impacted by operative time.
Indexed as
Identifiers
35821941PMC9210401What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.