Evidence map›Paper›PMID 35821515›Full record

ArticleNPJ digital medicine2022

Multi-center validation of machine learning model for preoperative prediction of postoperative mortality.

Seung Wook Lee, Hyung-Chul Lee, Jungyo Suh, Kyung Hyun Lee, Heonyi Lee, Suryang Seo, Tae Kyong Kim, Sang-Wook Lee, Yi-Jun Kim

Abstract read
In one paragraph

Article in NPJ digital medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 4 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Seung Wook LeeSchool of Medicine, Kyungpook National University, Daegu, Republic of Korea.ORCID http://orcid.org/0000-0003-4371-5703
Hyung-Chul LeeDepartment of Anesthesiology and Pain Medicine, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea.
Jungyo SuhDepartment of Urology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Kyung Hyun LeeDepartment of Digital Health, SAIHST, Sungkyunkwan University, Seoul, Republic of Korea.ORCID http://orcid.org/0000-0002-7010-5284
Heonyi LeeBioinformatics Collaboration Unit, Department of Biomedical Systems informatics, Yonsei University College of medicine, Seoul, Republic of Korea.
Suryang SeoDepartment of Nursing, SMG-SNU Boramae Medical Center, Seoul National University College of Medicine, Seoul, South Korea.
Tae Kyong KimDepartment of Anesthesiology and Pain Medicine, SMG-SNU Boramae Medical Center, Seoul National University College of Medicine, Seoul, South Korea.
Sang-Wook LeeDepartment of Anesthesiology and Pain Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea. sangwooklee20@gmail.com.ORCID http://orcid.org/0000-0003-2967-9670
Yi-Jun KimInstitute of Convergence Medicine, Ewha Womans University Mokdong Hospital, Seoul, Republic of Korea. yijunkim@ewha.ac.kr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Accurate prediction of postoperative mortality is important for not only successful postoperative patient care but also for information-based shared decision-making with patients and efficient allocation of medical resources. This study aimed to create a machine-learning prediction model for 30-day mortality after a non-cardiac surgery that adapts to the manageable amount of clinical information as input features and is validated against multi-centered rather than single-centered data. Data were collected from 454,404 patients over 18 years of age who underwent non-cardiac surgeries from four independent institutions. We performed a retrospective analysis of the retrieved data. Only 12-18 clinical variables were used for model training. Logistic regression, random forest classifier, extreme gradient boosting (XGBoost), and deep neural network methods were applied to compare the prediction performances. To reduce overfitting and create a robust model, bootstrapping and grid search with tenfold cross-validation were performed. The XGBoost method in Seoul National University Hospital (SNUH) data delivers the best performance in terms of the area under receiver operating characteristic curve (AUROC) (0.9376) and the area under the precision-recall curve (0.1593). The predictive performance was the best when the SNUH model was validated with Ewha Womans University Medical Center data (AUROC, 0.941). Preoperative albumin, prothrombin time, and age were the most important features in the model for each hospital. It is possible to create a robust artificial intelligence prediction model applicable to multiple institutions through a light predictive model using only minimal preoperative information that can be automatically extracted from each hospital.

Identifiers

PMID35821515
PMCPMC9276734

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.