ArticleInternational ophthalmology2022
Uveal melanoma and marital status: a relationship that affects survival.
Article in International ophthalmology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Associations of Social and Demographic Factors on the Outcomes of Ocular Melanoma and Other Adult Ocular Neoplasms in the United States: A Systematic Review.Cochrane evidence synthesis and methods · 2026Review
- Uveal melanoma survival prediction system: a multi-center database study.International ophthalmology · 2026Observational
- Longitudinal nationwide analysis of uveal melanoma in the United States1995-2018.International journal of clinical oncology · 2025Article
- A prognostic nomogram and risk classification system of elderly patients with extraosseous plasmacytoma: a SEER database analysis.Journal of cancer research and clinical oncology · 2023Article
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7 authors.
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Abstract
backgroundMarital status influences the presentation and outcome of various cancers. We explored the relationship between marital status and survival of uveal melanoma (UM) and factors influencing this relationship.
methodsWe conducted a retrospective cohort study on patients diagnosed with UM and registered in the Surveillance Epidemiology and End Results program between 1973 and 2017. Cox regression model was conducted to calculate the hazard ratio of overall and cancer-specific survival rate and delineate the effect of each confounder.
resultsThe study involved 10,557 patients with a male-to-female ratio of 1:1.1. Most of the diagnosed patients were aged between 40 and 79 years (81%). Married patients (62%) represented the majority, followed by singles (12%), widowed (11%), and then divorced patients (7%). Single patients were the youngest group (mean age of 59.3 years) while widowed patients were the oldest (mean age of 75.8 years). In the Cox regression model for overall survival, married and single patients exhibited the best overall survival (no significant difference in between them), both surpassing divorced and widowed patients. Married patients were at a significantly lower risk to die from UM than divorced patients. Female patients and younger age groups showed the best overall and cancer-specific survival.
conclusionMaintained marriages improved the survival of UM patients. Widowed and divorced patients should be included in specially designed support programs during their cancer management.
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