Evidence map›Paper›PMID 35821311›Full record

ArticleAnnals of nuclear medicine2022

Automated semi-quantitative amyloid PET analysis technique without MR images for Alzheimer's disease.

Etsuko Imabayashi, Naoyuki Tamamura, Yuzuho Yamaguchi, Yuto Kamitaka, Muneyuki Sakata, Kenji Ishii

Open access · hybridAbstract read
In one paragraph

Article in Annals of nuclear medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 27 citations in OpenAlex.

  1. Quantitative agreement between AMYclz and CortexID forJapanese journal of radiology · 2026
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  4. ATNIVS biomarker heterogeneity in real-world patients receiving lecanemab.The journal of prevention of Alzheimer's disease · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Etsuko Imabayashi *Research Team for Neuroimaging, Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology, 35-2 Sakae-cho, Itabashi-ku, Tokyo, 173-0015, Japan.
Naoyuki Tamamura *Nihon Medi-Physics Co., Ltd., 3-4-10 Shinsuna, Koto-ku, Tokyo, 136-0075, Japan.
Yuzuho YamaguchiNihon Medi-Physics Co., Ltd., 3-4-10 Shinsuna, Koto-ku, Tokyo, 136-0075, Japan.
Yuto KamitakaResearch Team for Neuroimaging, Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology, 35-2 Sakae-cho, Itabashi-ku, Tokyo, 173-0015, Japan.
Muneyuki SakataResearch Team for Neuroimaging, Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology, 35-2 Sakae-cho, Itabashi-ku, Tokyo, 173-0015, Japan.
Kenji IshiiResearch Team for Neuroimaging, Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology, 35-2 Sakae-cho, Itabashi-ku, Tokyo, 173-0015, Japan. ishii@pet.tmig.or.jp.ORCID http://orcid.org/0000-0002-2928-0072
Nihon Medi-Physics (Japan) · JPTokyo Metropolitan Geriatric Hospital · JPNational Institutes for Quantum Science and Technology · JPTokyo Metropolitan Institute of Gerontology · JP

Funding

Nihon MediPhysics, Co., Ltd. Collaboration Research
6 · The paper itself

Abstract

objectiveAlthough beta-amyloid (Aβ) positron emission tomography (PET) images are interpreted visually as positive or negative, approximately 10% are judged as equivocal in Alzheimer's disease. Therefore, we aimed to develop an automated semi-quantitative analysis technique using

methodsOverall, 136 cases of patients administered

resultsSUVr calculated by our method and CortexID were highly correlated (R

conclusionsThis semi-quantitative analysis technique using

Indexed as

Alzheimer DiseaseAmyloidosisAmyloidAmyloid beta-PeptidesAniline CompoundsBenzothiazolesBrainHumansPositron-Emission TomographyAmyloidAmyloid beta-PeptidesAniline CompoundsBenzothiazolesflutemetamol18F-flutemetamol-PETAlzheimer’s diseaseAutomated Aβ-PET analysisCentiloidSemi-quantitative Aβ analysis

Identifiers

PMID35821311
PMCPMC9515054
OpenAlexW4285095555

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.