ArticleScientific reports2022
Treadmill locomotion in the American alligator (Alligator mississippiensis) produces dynamic changes in intracranial cerebrospinal fluid pressure.
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 13 citations in OpenAlex.
- Temporal and spatial variations in CSF pressure are influenced by electrical stimulation of the OCI muscles in beagles.Scientific reports · 2025Article
- Anatomy of spinal CSF loss in the American alligator (Alligator mississippiensis).Journal of anatomy · 2025Article
- A review of cerebrospinal fluid circulation with respect to Chiari-like malformation and syringomyelia in brachycephalic dogs.Fluids and barriers of the CNS · 2025Review
- The presence of a foramen of Luschka in the American alligator (Alligator mississippiensis) and the continuity of the intraventricular and subdural spaces.Journal of anatomy · 2024Article
- Ambulatory intracranial pressure in humans: ICP increases during movement between body positions.Brain & spine · 2024Article
- The influence of spinal venous blood pressure on cerebrospinal fluid pressure.Scientific reports · 2023Article
- Dynamic asymmetry in cerebrospinal fluid pressure: An indicator of regional differences in compliance.Surgical neurology international · 2023Article
- The Influence of Movement on the Cerebrospinal Fluid Pressure of the American Alligator (Biology · 2022Article
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Authors and funding
2 authors at 1 institution in 1 country.
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Abstract
To examine the influence of movement on cerebrospinal fluid (CSF) dynamics, intracranial subdural pressure recordings were taken from sub-adult alligators (Alligator mississippiensis) locomoting on a treadmill. Pressure recordings documenting the cardiac, ventilatory, and barostatic influences on the CSF were in good agreement with previous studies. During locomotion the CSF exhibits sinusoidal patterns of pressure change that spanned a mean amplitude of 56 mm Hg, some 16 × the amplitude of the cardiac-linked pulsations. These sinusoidal CSF pulsations were closely linked to the locomotor kinematics, particularly the lateral oscillations of the alligator's head. Data recorded from the freely moving alligators suggest that fluid inertia, body cavity pressures, and likely other factors all influence the CSF pressure. The clear relationship between movement and CSF pressure described in this study suggests that the paucity of studies examining human CSF dynamics during movement should be addressed.
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