Evidence map›Paper›PMID 35821228›Full record

ArticleScientific reports2022

Higher hair cortisol concentrations associated with shorter leukocyte telomere length in high-risk young adults.

David Bürgin, Nimmy Varghese, Anne Eckert, Vera Clemens, Eva Unternährer, Cyril Boonmann, Aoife O'Donovan, Marc Schmid

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
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  3. Differential effects of childhood maltreatment types and timing on psychopathology in formerly out-of-home placed young adults.European psychiatry : the journal of the Association of European Psychiatrists · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

David BürginPsychiatric University Hospitals, Child and Adolescent Psychiatric Research Department (UPKKJ), University of Basel, Basel, Switzerland. david.buergin@upk.ch.
Nimmy VargheseNeurobiological Laboratory for Brain Aging and Mental Health, Transfaculty Research Platform, University of Basel, Basel, Switzerland.
Anne EckertNeurobiological Laboratory for Brain Aging and Mental Health, Transfaculty Research Platform, University of Basel, Basel, Switzerland.
Vera ClemensDepartment for Child and Adolescent Psychiatry/Psychotherapy, University Hospital Ulm, Ulm, Germany.
Eva UnternährerPsychiatric University Hospitals, Child and Adolescent Psychiatric Research Department (UPKKJ), University of Basel, Basel, Switzerland.
Cyril BoonmannPsychiatric University Hospitals, Child and Adolescent Psychiatric Research Department (UPKKJ), University of Basel, Basel, Switzerland.
Aoife O'DonovanDepartment of Psychiatry and Weill Institute for Neurosciences, University of California San Francisco, San Francisco, USA.
Marc SchmidPsychiatric University Hospitals, Child and Adolescent Psychiatric Research Department (UPKKJ), University of Basel, Basel, Switzerland.
University of Basel · CHUniversity Hospital Ulm · DEUniversity of California, San Francisco · US

Funding

Effects of inflammation on neural mechanisms of threat sensitivity in posttraumatic stress disorderK01MH109871 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI O'DONOVAN, AOIFE · 2016 to 2019
$737k
NIMH NIH HHS K01 MH109871
6 · The paper itself

Abstract

Chronic stress is associated with accelerated biological aging as indexed by short age-adjusted leukocyte telomere length (LTL). Exploring links of biological stress responses with LTL has proved challenging due to the lack of biological measures of chronic psychological stress. Hair cortisol concentration (HCC) has emerged as a measure of chronic hypothalamic pituitary adrenal (HPA) axis activation, allowing the examination of relationships between aggregate cortisol concentrations over time and LTL. Our sample includes 92 participants (38% women, M

Indexed as

HydrocortisoneLeukocytesAdultFemaleHairHumansMalePituitary-Adrenal SystemTelomereYoung AdultHydrocortisone

Identifiers

PMID35821228
PMCPMC9276815
OpenAlexW4285095579

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.