Evidence map›Paper›PMID 35821076›Full record

ArticleEcho research and practice2022

Echocardiographic description and outcomes in a heterogeneous cohort of patients undergoing mitral valve surgery with and without mitral annular disjunction: a health service evaluation.

Sadie Bennett, Jacopo Tafuro, Marcus Brumpton, Caragh Bardolia, Grant Heatlie, Simon Duckett, Paul Ridley, Prakash Nanjaiah, Chun Shing Kwok

Open access · goldAbstract read
In one paragraph

Article in Echo research and practice, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Mitral Valve Surgery with and Without Mitral Annular Disjunction: A Meta-Analysis.Journal of cardiovascular development and disease · 2025
    Review
  3. Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Sadie BennettHeart and Lung Centre, University Hospitals of North Midlands, Stoke-on-Trent, ST4 6QG, UK. Sadie.Bennett@UHNM.nhs.uk.
Jacopo TafuroHeart and Lung Centre, University Hospitals of North Midlands, Stoke-on-Trent, ST4 6QG, UK.
Marcus BrumptonHeart and Lung Centre, University Hospitals of North Midlands, Stoke-on-Trent, ST4 6QG, UK.
Caragh BardoliaHeart and Lung Centre, University Hospitals of North Midlands, Stoke-on-Trent, ST4 6QG, UK.
Grant HeatlieHeart and Lung Centre, University Hospitals of North Midlands, Stoke-on-Trent, ST4 6QG, UK.
Simon DuckettHeart and Lung Centre, University Hospitals of North Midlands, Stoke-on-Trent, ST4 6QG, UK.
Paul RidleyHeart and Lung Centre, University Hospitals of North Midlands, Stoke-on-Trent, ST4 6QG, UK.
Prakash NanjaiahHeart and Lung Centre, University Hospitals of North Midlands, Stoke-on-Trent, ST4 6QG, UK.
Chun Shing KwokHeart and Lung Centre, University Hospitals of North Midlands, Stoke-on-Trent, ST4 6QG, UK.
University Hospitals of North Midlands NHS Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMitral annular disjunction (MAD) is a structural abnormality characterized by the distinct separation of the mitral valve annulus/left atrium wall and myocardium. Little is known about the significance of MAD in patients requiring mitral valve surgery. This evaluation evaluates the echocardiographic characteristics and patient outcomes for patients with and without MAD who require mitral valve surgery.

methodsAll patients who underwent mitral valve surgery and who had a pre-surgical transthoracic echocardiogram between 2013 and 2020 were included. Patient demographics and clinical outcomes were collected on review of patient electronic records.

resultsA total of 185 patients were included in the analysis of which 32.4% had MAD (average MAD length 8.4 mm). MAD was seen most commonly in patients with mitral valve prolapse and myxomatous mitral valves disease (90% and 60% respectively). In the patients with MAD prior to mitral valve surgery, only 3.9% had MAD post mitral valve surgery. There were no significant difference in the severity of post-operative mitral regurgitation, arrhythmic events or major adverse cardiovascular events in patients with and without MAD.

conclusionsMAD is common in patients who undergo mitral valve surgery. Current surgical techniques are able to correct the MAD abnormality in the vast majority of patients. MAD is not associated with an increased risk of adverse clinical outcomes post mitral valve surgery.

Indexed as

Clinical outcomesMitral annular disjunctionMitral valve surgery

Identifiers

PMID35821076
PMCPMC9277900
OpenAlexW4285086370

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.