Evidence map›Paper›PMID 35820992›Full record

ArticleEvidence-based mental health2022

Effectiveness and cost-effectiveness of universal school-based mindfulness training compared with normal school provision in reducing risk of mental health problems and promoting well-being in adolescence: the MYRIAD cluster randomised controlled trial.

Willem Kuyken, Susan Ball, Catherine Crane, Poushali Ganguli, Benjamin Jones, Jesus Montero-Marin, Elizabeth Nuthall, Anam Raja, Laura Taylor, Kate Tudor and 29 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Evidence-based mental health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 116 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
116citing papers in PubMed, 2 pooled it
43.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

116 citing papers in PubMed, 2 syntheses or guidelines pooled it, 242 citations in OpenAlex.

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  4. Cost Analysis of BEST in CLASS-Elementary: Average Cost per Teacher-Student Dyad and Marginal Cost per Additional Student.Prevention science : the official journal of the Society for Prevention Research · 2026
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  13. Promoting 21st Century Health and Wellness Skills in Elementary School Children: a Group Randomized Trial.Prevention science : the official journal of the Society for Prevention Research · 2024
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  14. Promoting 21st Century Health and Wellness Skills in Elementary School Children: a Group Randomized Trial.Prevention science : the official journal of the Society for Prevention Research · 2024
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  20. Student- and School-Level Factors Associated With Mental Health and Well-Being in Early Adolescence.Journal of the American Academy of Child and Adolescent Psychiatry · 2024
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56 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

39 authors at 7 institutions in 3 countries.

Willem KuykenDepartment of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK willem.kuyken@psych.ox.ac.uk.ORCID http://orcid.org/0000-0002-8596-5252
Susan BallNIHR Applied Research Collaboration South West Peninsula (PenARC), University of Exeter, Exeter, Devon, UK.ORCID http://orcid.org/0000-0002-9937-4832
Catherine CraneDepartment of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK.
Poushali GanguliKing's College London, King's Health Economics, Institute of Psychiatry, Psychology and Neuroscience, De Crespigny Park, London, UK.
Benjamin JonesNIHR Applied Research Collaboration South West Peninsula (PenARC), University of Exeter, Exeter, Devon, UK.
Jesus Montero-MarinDepartment of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK.ORCID http://orcid.org/0000-0001-5677-1662
Elizabeth NuthallDepartment of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK.
Anam RajaDepartment of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK.
Laura TaylorDepartment of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK.
Kate TudorDepartment of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK.
Russell M VinerPopulation, Policy & Practice research programme, UCL Great Ormond St. Institute of Child Health, London, UK.ORCID http://orcid.org/0000-0003-3047-2247
Matthew AllwoodDepartment of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK.
Louise AuklandDepartment of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK.
Darren DunningMedical Research Council Cognition and Brain Sciences Unit, University of Cambridge, Cambridge, UK.
Tríona CaseyDepartment of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK.ORCID http://orcid.org/0000-0002-7789-9072
Nicola DalrympleDepartment of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK.
Katherine De WildeDepartment of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK.
Eleanor-Rose FarleyDepartment of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK.
Jennifer HarperDepartment of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK.
Nils KappelmannDepartment of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK.
Maria KempnichDepartment of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK.
Liz LordDepartment of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK.
Emma MedlicottDepartment of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK.
Lucy PalmerDepartment of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK.
Ariane PetitDepartment of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK.
Alice PhilipsDepartment of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK.
Isobel Pryor-NitschDepartment of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK.
Lucy RadleyDepartment of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK.
Anna SonleyDepartment of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK.
Jem ShacklefordDepartment of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK.
Alice TickellDepartment of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK.
Sarah-Jayne BlakemoreDepartment of Psychology, University of Cambridge, Cambridge, UK.
The Myriad TeamDepartment of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK.
Obioha C UkoumunneNIHR Applied Research Collaboration South West Peninsula (PenARC), University of Exeter, Exeter, Devon, UK.
Mark T GreenbergDepartment of Human Development and Family Studies, The Pennsylvania State University, University Park, Pennsylvania, USA.
Tamsin FordDepartment of Psychiatry, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK.
Tim DalgleishMedical Research Council Cognition and Brain Sciences Unit, University of Cambridge, Cambridge, UK.
Sarah ByfordKing's College London, King's Health Economics, Institute of Psychiatry, Psychology and Neuroscience, De Crespigny Park, London, UK.ORCID http://orcid.org/0000-0001-7084-1495
J Mark G WilliamsDepartment of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK.
Warneford Hospital · GBUniversity of Exeter · GBKing's College London · GBMRC Cognition and Brain Sciences Unit · GBUniversity of Cambridge · GBGreat Ormond Street Hospital · GBPennsylvania State University · US

Funding

Medical Research Council MC_UU_00030/5Wellcome Trust
6 · The paper itself

Abstract

backgroundSystematic reviews suggest school-based mindfulness training (SBMT) shows promise in promoting student mental health.

objectiveThe My Resilience in Adolescence (MYRIAD) Trial evaluated the effectiveness and cost-effectiveness of SBMT compared with teaching-as-usual (TAU).

methodsMYRIAD was a parallel group, cluster-randomised controlled trial. Eighty-five eligible schools consented and were randomised 1:1 to TAU (43 schools, 4232 students) or SBMT (42 schools, 4144 students), stratified by school size, quality, type, deprivation and region. Schools and students (mean (SD); age range=12.2 (0.6); 11-14 years) were broadly UK population-representative. Forty-three schools (n=3678 pupils; 86.9%) delivering SBMT, and 41 schools (n=3572; 86.2%) delivering TAU, provided primary end-point data. SBMT comprised 10 lessons of psychoeducation and mindfulness practices. TAU comprised standard social-emotional teaching. Participant-level risk for depression, social-emotional-behavioural functioning and well-being at 1 year follow-up were the co-primary outcomes. Secondary and economic outcomes were included.

findingsAnalysis of 84 schools (n=8376 participants) found no evidence that SBMT was superior to TAU at 1 year. Standardised mean differences (intervention minus control) were: 0.005 (95% CI -0.05 to 0.06) for risk for depression; 0.02 (-0.02 to 0.07) for social-emotional-behavioural functioning; and 0.02 (-0.03 to 0.07) for well-being. SBMT had a high probability of cost-effectiveness (83%) at a willingness-to-pay threshold of £20 000 per quality-adjusted life year. No intervention-related adverse events were observed.

conclusionsFindings do not support the superiority of SBMT over TAU in promoting mental health in adolescence. CLINICAL IMPLICATIONS: There is need to ask what works, for whom and how, as well as considering key contextual and implementation factors.

trial registrationCurrent controlled trials ISRCTN86619085. This research was funded by the Wellcome Trust (WT104908/Z/14/Z and WT107496/Z/15/Z).

Indexed as

Child & adolescent psychiatryDepression & mood disorders

Identifiers

PMID35820992
PMCPMC9340028
OpenAlexW4285094133

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.