Evidence map›Paper›PMID 35820952›Full record

ArticleJournal of cannabis research2022

Online information on medical cannabis is not always aligned with scientific evidence and may raise unrealistic expectations.

Arthur Cassa Macedo, André Oliveira Vilela de Faria, Isabella Bizzi, Fabrício A Moreira, Alessandro Colasanti, Pietro Ghezzi

Abstract read
In one paragraph

Article in Journal of cannabis research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Cannabis and Cannabinoids in Adults With Cancer: ASCO Guideline.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Arthur Cassa MacedoUniversidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
André Oliveira Vilela de FariaUniversidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
Isabella BizziUniversidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil.
Fabrício A MoreiraUniversidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
Alessandro ColasantiBrighton & Sussex Medical School, Trafford Centre, University of Sussex, Falmer, Brighton, East Sussex, BN1 9RY, UK.
Pietro GhezziBrighton & Sussex Medical School, Trafford Centre, University of Sussex, Falmer, Brighton, East Sussex, BN1 9RY, UK. p.ghezzi@bsms.ac.uk.ORCID http://orcid.org/0000-0003-0911-8358

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere is a growing literature on the potential medical uses of Cannabis sativa and cannabinoid compounds. Although these have only been approved by regulatory agencies for a few indications, there is a hype about their possible benefits in a variety of conditions and a large market in the wellness industry. As in many cases patients search for information on cannabis products online, we have analyzed the information on medical cannabis available on the Internet. Therefore, this study aims at assessing the quality of the information available online on medical cannabis.

methodsWe searched "medical cannabis" on June 2019 using google.com and downloaded the first 243 websites. After excluding dead links or websites with no information about cannabis, 176 websites were included. They were then classified for their typology (e.g., commercial, government, news outlets). As an indicator of trustworthiness, we used the Journal of American Medical Association (JAMA) score, which assesses the indication of date, author, ownership of the website, and the presence of references. We also considered if a website is certified by Health-On-the-Net (HON), an independent organization, by displaying a HONCode symbol. Subsequently, we performed a content analysis to assess both the medical cannabis indications mentioned by webpages and the completeness of the information provided (whether they mentioned potential side effects and legal/regulatory issues or not).

resultsAnalyzing 176 webpages returned by a search engine, we found that 52% of them were news websites. Pain, epilepsy, and multiple sclerosis were the most frequently mentioned therapeutic areas (cited in 92, 84 and 80 webpages, respectively), which did not always match those for which there is regulatory approval. Information was also incomplete, with only 22% of the webpages mentioning potential side effects. Health portal websites provided the most complete information, with all of them (n = 7) reporting side effects. On average, 80% of webpages had a neutral stance on the potential benefits of medical cannabis, with commercial websites having more frequently a positive stance (67%).

conclusionsWe conclude that the information that can be found online is not always aligned in terms of the therapeutic areas for which science-based evidence is often still weak.

Indexed as

CannabisConsumer health informationHealth informationWebsites

Identifiers

PMID35820952
PMCPMC9277882

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.