SynthesisBMC medical research methodology2022
Meta-analysis using Python: a hands-on tutorial.
Synthesis in BMC medical research methodology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 9 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 9 syntheses or guidelines pooled it.
- Robot-assisted versus laparoscopic surgery for rectal cancer: a systematic review and meta-analysis of randomised trials with GRADE certainty rating.Surgical endoscopy · 2026Pooled it
- Effectiveness of interventions using activity trackers and smartphone applications for increasing physical activity in older adults with health conditions: a systematic review with meta-analysis.The Journal of frailty & aging · 2026Pooled it
- Endoscopic versus open vein harvesting for coronary artery bypass: a systematic review and meta-analysis.Journal of cardiothoracic surgery · 2025Pooled it
- A meta-analysis of vaccine efficacy from phase III clinical trials of approved vaccines against SARS-CoV-2 and variants.BMC infectious diseases · 2025Pooled it
- Comparative Effectiveness of Digital Health Technologies in Tuberculosis Treatment: Systematic Review and Network Meta-Analysis of Randomized Controlled Trials.JMIR mHealth and uHealth · 2025Pooled it
- Preventive clipping versus coiling in unruptured intracranial aneurysms: A comprehensive meta-analysis and systematic review to explore safety and efficacy.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025Pooled it
- Second-Hand Smoke Exposure and Risk of Lung Cancer Among Nonsmokers in the United States: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2025Pooled it
- Strokecopilot: a literature-based clinical decision support system for acute ischemic stroke treatment.Journal of neurology · 2023Pooled it
- A meta-evaluation of the quality of reporting and execution in ecological meta-analyses.PloS one · 2023Pooled it
- COmprehensive Meta-analysis and meta-regression of Psychiatric disorders in people with Amphetamine-type Stimulant use disorder Study (COMPASS): a protocol for a pilot study, a systematic review and a meta-analysis series.Systematic reviews · 2026Article
- ND-AMD: A Web-Based Database for Animal Models of Neurological Disease With Analysis Tools.CNS neuroscience & therapeutics · 2025Article
- Diagnostic value of preoperative examination for evaluating margin status in breast cancer.World journal of clinical cases · 2023Article
- Knowledge in Motion: A Comprehensive Review of Evidence-Based Human Kinetics.International journal of environmental research and public health · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMeta-analysis is a central method for quality evidence generation. In particular, meta-analysis is gaining speedy momentum in the growing world of quantitative information. There are several software applications to process and output expected results. Open-source software applications generating such results are receiving more attention. This paper uses Python's capabilities to provide applicable instruction to perform a meta-analysis.
methodsWe used the PythonMeta package with several modifications to perform the meta-analysis on an open-access dataset from Cochrane. The analyses were complemented by employing Python's zEpid package capable of creating forest plots. Also, we developed Python scripts for contour-enhanced funnel plots to assess funnel plots asymmetry. Finally, we ran the analyses in R and STATA to check the cross-validity of the results.
resultsA stepwise instruction on installing the software and packages and performing meta-analysis was provided. We shared the Python codes for meta-analysts to follow and generate the standard outputs. Our results were similar to those yielded by R and STATA.
conclusionWe successfully produced standard meta-analytic outputs using Python. This programming language has several flexibilities to improve the meta-analysis results even further.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.