Evidence map›Paper›PMID 35820845›Full record

Trial reportBMC palliative care2022

Do surrogates predict patient preferences more accurately after a physician-led discussion about advance directives? A randomized controlled trial.

Catarina Sampaio Martins, Iva Sousa, Cláudia Barros, Alexandra Pires, Luisa Castro, Cristina da Costa Santos, Rui Nunes

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC palliative care, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05090072 (Advanced Directives in Palliative Care), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05090072 nacompletednot on this map

Advanced Directives in Palliative Care: Physician's Role on Caregiver's Empowerment as Patient's Surrogates

TypeinterventionalSponsorUniversidade do PortoRan2018 to 2021Enrolled116ConditionsEnd-of-lifeArmsAdvance Directives, Control
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Advance Directives in Portugal: A Qualitative Survey.Healthcare (Basel, Switzerland) · 2024
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Catarina Sampaio MartinsPalliative Medicine Service of Centro Hospitalar de Tràs-Os-Montes E Alto Douro, 5000-508, Vila Real, Portugal. catarinasamp@gmail.com.ORCID http://orcid.org/0000-0002-4505-1608
Iva SousaPalliative Medicine Service of Centro Hospitalar de Tràs-Os-Montes E Alto Douro, 5000-508, Vila Real, Portugal.ORCID http://orcid.org/0000-0002-5436-4155
Cláudia BarrosPalliative Medicine Service of Centro Hospitalar de Tràs-Os-Montes E Alto Douro, 5000-508, Vila Real, Portugal.ORCID http://orcid.org/0000-0001-5281-1188
Alexandra PiresPalliative Medicine Service of Centro Hospitalar de Tràs-Os-Montes E Alto Douro, 5000-508, Vila Real, Portugal.ORCID http://orcid.org/0000-0003-0624-5538
Luisa CastroMEDCIDS-Department of Community Medicine, Information and Decision in Health, University of Porto, 4200-450, Porto, Portugal.ORCID http://orcid.org/0000-0002-1312-0154
Cristina da Costa SantosDepartment of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine, MEDCIDS, University of Porto, Rua Dr. Plácido da Costa, 4200-319, Porto, Portugal.ORCID http://orcid.org/0000-0002-7109-1101
Rui NunesFaculty of Medicine, MEDCIDS-Department of Community Medicine, Information and Decision in Health, University of Porto, 4200-450, Porto, Portugal.ORCID http://orcid.org/0000-0002-1377-9899
Unidade Local de Saúde de Trás-os-Montes e Alto Douro · PTUniversidade do Porto · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCaregivers frequently assume the role of surrogate decision-makers but often are unable to accurately predict patients' preferences. This trial aims to find if the use of the Advance Directives documents as a communication tool, improves the agreement between patients and caregivers.

methodsThis trial occurred in a palliative care service of a Portuguese hospital center. A prospective, single-blinded, controlled, randomized trial, enrolling patients and caregivers as a dyad was conducted. Participants individually fulfilled an Advance Directive document, in which patients reported their end-of-life preferences and caregivers reported their decisions as patients' health surrogates. Dyads were randomly assigned to the Intervention or the Control group, in which the physician respectively promoted an open discussion about patients' Advance Directives or evaluated patients' clinical condition. Caregivers' Advance Directives as surrogates were collected one month later. Proportions of agreement and Cohen's κ were used to access agreement and reliability, respectively, between the dyads.

resultsResults from 58 dyads were analyzed. We observed an improvement in agreement between the caregivers' answers and the patients' wishes on two-thirds (8/12) of the answers, in the Intervention group, contrasting to one-quarter (3/12) of the answers, in the Control group, despite statistical significance in differences wasn´t obtained.

conclusionsAlthough not reaching statistical significance, the results suggest that discussions of advance directives with physicians may lead to better prepared surrogates.

trial registrationClinicalTrials.gov ID NCT05090072 . Retrospectively registered on 22/10/2021.

Indexed as

Patient PreferencePhysiciansAdvance DirectivesHumansProspective StudiesReproducibility of ResultsAdvance DirectivesCaregiversDecision-makingPalliative Care

Identifiers

PMID35820845
PMCPMC9277787
OpenAlexW4285093054

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.