Evidence map›Paper›PMID 35820713›Full record

Trial reportBMJ open quality2022

Early detection and treatment of acute illness in medical patients with novel software: a prospective quality improvement initiative.

Jonathan Burns, Dave Williams, Danielle Mlinaritsch, Maryna Koechlin, Trena Canning, Andrew Neitzel

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMJ open quality, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 2 pooled it
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 syntheses or guidelines pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jonathan BurnsAbbotsford Regional Hospital and Cancer Centre, Abbotsford, British Columbia, Canada.
Dave WilliamsAbbotsford Regional Hospital and Cancer Centre, Abbotsford, British Columbia, Canada.
Danielle MlinaritschAbbotsford Regional Hospital and Cancer Centre, Abbotsford, British Columbia, Canada.
Maryna KoechlinAbbotsford Regional Hospital and Cancer Centre, Abbotsford, British Columbia, Canada.
Trena CanningAbbotsford Regional Hospital and Cancer Centre, Abbotsford, British Columbia, Canada.
Andrew NeitzelAbbotsford Regional Hospital and Cancer Centre, Abbotsford, British Columbia, Canada andy.neitzel@gmail.com.ORCID 0000-0002-7010-6359
Abbotsford Veterinary Clinic · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveAn ageing population and rising healthcare costs place healthcare systems at risk of failure. Our goal was to develop a technology that would identify illness early, initiate action and therein improve patient care, outcomes and save healthcare resources.

designThis was a prospective interventional quality improvement study.

settingA 40 bed medical floor in a 300 bed Canadian tertiary care regional referral hospital.

participantsGeneral ward patients randomly assigned to control or treatment groups. There was no cross-over or loss to follow-up.

interventionWe designed an algorithm and software programme capable of detecting the sentinel change in a deteriorating patient's clinical condition and once detected direct early investigation and care. Study duration was 1 year.

main outcome measuresPrimary outcome was patient transfer from the general medical ward to the intensive care unit (ICU). The secondary outcome was the time needed to (1) order investigations (2) contact senior medical staff and (3) senior medical staff intervention.

resultsWe identified a decrease in the transfer of patients from the medical ward to the ICU. Over the course of the study including 273 patients (110 in the control group and 163 in the treatment group), transfers dropped from 14 to 3 with a relative risk reduction of 85.54% (95% CI 84.96 to 86.1), a number needed to treat of 9.19 (95% CI 9.01 to 9.36) and a absolute risk reduction of 10.89% (95% CI 10.7 to 11.1). We also found a statistically significant reduction in the time required to order investigations (p=0.049), contact senior medical staff (p=0.040) and senior medical staff intervention (p=0.045).

conclusionA novel algorithm and software in the hands of nursing staff identified acute illness with adequate sensitivity and specificity to dramatically reduce ICU transfers and time to clinical intervention on a medical ward.

Indexed as

Quality ImprovementSoftwareAcute DiseaseCanadaHumansProspective StudiesTertiary Care Centersartificial Intelligenceclinical decision-makingcritical caredecision makingdecision support, clinical

Identifiers

PMID35820713
PMCPMC9277399
OpenAlexW4285098307

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.