Evidence map›Paper›PMID 35820664›Full record

Trial reportThe Medical journal of Australia2022

The acceptability and usability of two HIV self-test kits among men who have sex with men: a randomised crossover trial.

Dana Yl Lee, Jason J Ong, Kirsty Smith, Muhammad S Jamil, Ruthy McIver, Rebecca Wigan, Kate Maddaford, Anna McNulty, John M Kaldor, Christopher K Fairley and 9 more

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in The Medical journal of Australia, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Review
  3. Preferences for oral-World journal of methodology · 2023
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

19 authors.

Dana Yl LeeCentral Clinical School, Monash University, Melbourne, VIC.ORCID 0000-0002-2136-7632
Jason J OngCentral Clinical School, Monash University, Melbourne, VIC.ORCID 0000-0001-5784-7403
Kirsty SmithKirby Institute, University of New South Wales, Sydney, NSW.
Muhammad S JamilGlobal HIV, Hepatitis and STI Programmes, World Health Organization, Geneva, Switzerland.
Ruthy McIverSydney Sexual Health Centre, Sydney, NSW.
Rebecca WiganMelbourne Sexual Health Centre Alfred Health, Melbourne, VIC.
Kate MaddafordMelbourne Sexual Health Centre Alfred Health, Melbourne, VIC.
Anna McNultySydney Sexual Health Centre, Sydney, NSW.
John M KaldorKirby Institute, University of New South Wales, Sydney, NSW.
Christopher K FairleyMelbourne Sexual Health Centre Alfred Health, Melbourne, VIC.
Benjamin BavintonCentral Clinical School, Monash University, Melbourne, VIC.
Marcus ChenCentral Clinical School, Monash University, Melbourne, VIC.
Eric Pf ChowCentral Clinical School, Monash University, Melbourne, VIC.ORCID 0000-0003-1766-0657
Andrew E GrulichKirby Institute, University of New South Wales, Sydney, NSW.
Martin HoltKirby Institute, University of New South Wales, Sydney, NSW.
Damian P ConwayKirby Institute, University of New South Wales, Sydney, NSW.ORCID 0000-0003-3316-2199
Mark StooveThe Burnet Institute, Melbourne, VIC.
Handan WandKirby Institute, University of New South Wales, Sydney, NSW.
Rebecca J GuyKirby Institute, University of New South Wales, Sydney, NSW.

Funding

World Health Organization 001
6 · The paper itself

Abstract

objectivesTo compare the usability and acceptability of oral fluid- and blood-based HIV self-test kits among men who have sex with men in Australia.

designRandomised crossover trial. SETTING,

participantsGay, bisexual, and other men aged 18 years or older who have sex with men, who attended two metropolitan sexual health clinics in Sydney and Melbourne, 7 January - 10 December 2019.

main outcome measuresEase of use of HIV self-test kits; preferred HIV self-test type; difficulties encountered during HIV self-testing.

results170 men were recruited (median age, 34 years; interquartile range, 29-43 years); 144 identified as gay (85%), 96 were born outside Australia (57%). Participants were more likely to report the oral fluid HIV self-test was easy to use than the blood-based self-test (oral fluid, 99%; blood, 86%; odds ratio [OR], 3.0; 95% confidence interval [CI], 1.4-6.6). The oral fluid test was preferred by 98 participants (58%; 95% CI, 50-65%), the blood-based test by 69 (41%; 95% CI, 33-48%). Difficulties with the oral fluid test kit identified by observing nurses included problems placing the buffer solution into the stand (40 of 170 participants, 24%) and not swabbing both gums (23 of 169, 14%); difficulties with the blood-based test kit included problems filling the device test channel (69 of 170, 41%) and squeezing the finger firmly enough to generate a blood drop (42 of 170, 25%). No participant received an invalid result with the oral fluid self-test; two of 162 participants (1%) received invalid results with the blood self-test. After adjusting for age, education level, and ethnic background, characteristics associated with higher odds of using HIV self-testing in the future were overseas birth (adjusted OR, 3.07; 95% CI, 1.42-6.64), and self-evaluated ease of use and confidence in using the kits.

conclusionIt is important to provide options for obtaining both oral fluid- and blood-based HIV self-tests. The usability and acceptability of both kits were high, but the ease of use and perceived accuracy influenced test kit preference.

Indexed as

HIV InfectionsSexual and Gender MinoritiesAdultCross-Over StudiesHomosexuality, MaleHumansMaleSelf-TestingDiagnostic tests and proceduresHIVPublic healthSexually transmitted diseases

Identifiers

PMID35820664
PMCPMC9542976

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.