Evidence map›Paper›PMID 35820015›Full record

ArticleIEEE transactions on ultrasonics, ferroelectrics, and frequency control2022

High-Frequency Ultrasound Elastography to Assess the Nonlinear Elastic Properties of the Cornea and Ciliary Body.

Junhang Zhang, Javier Murgoitio-Esandi, Xuejun Qian, Runze Li, Chen Gong, Amir Nankali, Liang Hao, Benjamin Y Xu, K Kirk Shung, Assad Oberai and 1 more

Open access · greenAbstract read
In one paragraph

Article in IEEE transactions on ultrasonics, ferroelectrics, and frequency control, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Junhang Zhang
Javier Murgoitio-Esandi
Xuejun Qian
Runze Li
Chen Gong
Amir Nankali
Liang Hao
Benjamin Y Xu
K Kirk Shung
Assad Oberai
Qifa Zhou
University of Southern California · US

Funding

Ophthalmic Therapeutics Engineering CoreP30EY029220 · NEI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Mahnaz Shahidi · 2018 to 2026
$6.5M
High-resolution Elastographic Assessment of the Optic Nerve HeadR01EY028662 · NEI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI CHEN, ZHONGPING, SIGAL, IAN A · 2018 to 2021
$2.7M
Biomechanical mapping of the optic nerve head and peripapillary sclera using high frequency ultrasonic elastographyR01EY032229 · NEI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI ZHOU, QIFA · 2021 to 2024
$2.6M
Non-invasive Ultrasound Stimulated Retinal ProsthesisR01EY030126 · NEI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI ZHOU, QIFA · 2019 to 2022
$2.0M
Development and Validation of Quantitative Anterior Segment OCT-based Methods to Evaluate Patients with Primary Angle Closure DiseaseK23EY029763 · NEI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI XU, BENJAMIN Y. · 2019 to 2023
$1.1M
NEI NIH HHS K23 EY029763NEI NIH HHS P30 EY029220NEI NIH HHS R01 EY028662NEI NIH HHS R01 EY030126NEI NIH HHS R01 EY032229
6 · The paper itself

Abstract

Mechanical properties of the anterior anatomical structures of the eye, such as the cornea and ciliary body, play a key role in the ocular function and homeostasis. However, measuring the biomechanical properties of the anterior ocular structures, especially deeper structures, such as the ciliary body, remains a challenge due to the lack of high-resolution imaging tools. Herein, we implement a mechanical shaker-based high-frequency ultrasound elastography technique that can track the induced elastic wave propagation to assess the linear and nonlinear elastic properties of anterior ocular structures. The findings of this study advance our understanding of the role of anterior ocular structures in the pathogenesis of different ocular disorders, such as glaucoma.

Indexed as

Ciliary BodyElasticity Imaging TechniquesCornea

Identifiers

PMID35820015
PMCPMC9547080
OpenAlexW4285077023

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.