Evidence map›Paper›PMID 35819587›Full record

SynthesisJournal of autism and developmental disorders2023

Characterizing Interoceptive Differences in Autism: A Systematic Review and Meta-analysis of Case-control Studies.

Zachary J Williams, Evan Suzman, Samantha L Bordman, Jennifer E Markfeld, Sophia M Kaiser, Kacie A Dunham, Alisa R Zoltowski, Michelle D Failla, Carissa J Cascio, Tiffany G Woynaroski

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Journal of autism and developmental disorders, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Associations Between Autism and Self-Reported Dimensions of Interoception.Autism : the international journal of research and practice · 2026
    Article
  6. Article
  7. Review and Developmental Model: Early Childhood Emotion Regulation and Co-Regulation in Autism.Journal of the American Academy of Child and Adolescent Psychiatry · 2026
    Review
  8. Article
  9. Review
  10. Autism care: reimagining the spectrum.Frontiers in child and adolescent psychiatry · 2026
    Article
  11. The inner life of autism: a call to action.Frontiers in pediatrics · 2026
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Trait and state mathematics anxiety in autistic and non-autistic school-aged boys.Autism : the international journal of research and practice · 2025
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Zachary J WilliamsMedical Scientist Training Program, Vanderbilt University School of Medicine, Nashville, TN, USA. Zachary.j.williams@vanderbilt.edu.ORCID http://orcid.org/0000-0001-7646-423X
Evan Suzman *UT Southwestern Medical School, Dallas, TX, USA.
Samantha L BordmanVA Pittsburgh Medical Center, Pittsburgh, PA, USA.
Jennifer E MarkfeldDepartment of Hearing and Speech Sciences, Vanderbilt University Medical Center, 1215 21st Avenue South, Medical Center East, South Tower, Room 8310, Nashville, TN, 37232, USA.
Sophia M KaiserUndergraduate Programs in Cognitive Studies and Medicine, Health, and Society, Vanderbilt University, Nashville, TN, USA.
Kacie A DunhamDepartment of Hearing and Speech Sciences, Vanderbilt University Medical Center, 1215 21st Avenue South, Medical Center East, South Tower, Room 8310, Nashville, TN, 37232, USA.
Alisa R ZoltowskiVanderbilt Brain Institute, Vanderbilt University, Nashville, TN, USA.
Michelle D FaillaCollege of Nursing, The Ohio State University, Columbus, OH, USA.
Carissa J CascioVanderbilt Brain Institute, Vanderbilt University, Nashville, TN, USA.
Tiffany G WoynaroskiDepartment of Hearing and Speech Sciences, Vanderbilt University Medical Center, 1215 21st Avenue South, Medical Center East, South Tower, Room 8310, Nashville, TN, 37232, USA.

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM007347 · NIGMS · VANDERBILT UNIVERSITY · PI WILLIAMS, CHRISTOPHER S. · 1985 to 2023
$26.3M
Overall: Eunice Kennedy Shriver Intellectual and Developmental Disabilities Research Center at VanderbiltP50HD103537 · NICHD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Lea K Davis · 2020 to 2026
$10.3M
Medical Scientist Training ProgramT32GM152284 · NIGMS · VANDERBILT UNIVERSITY · PI Christopher S. Williams · 2024 to 2026
$4.8M
Sensorimotor integration governing facial expression production in autism.R01MH102272 · NIMH · VANDERBILT UNIVERSITY MEDICAL CENTER · PI CASCIO, CARISSA J · 2014 to 2023
$4.3M
Investigating the Phenomenology and Physiologic Underpinnings of Decreased Sound Tolerance in Adults with Autism Spectrum DisorderF30DC019510 · NIDCD · VANDERBILT UNIVERSITY · PI WILLIAMS, ZACHARY JAMES · 2021 to 2024
$163k
Looking to and Processing of Audiovisual Speech in Infants at Risk for AutismF31DC020129 · NIDCD · VANDERBILT UNIVERSITY · PI DUNHAM-CARR, KACIE · 2021 to 2024
$89k
NICHD NIH HHS P50 HD103537NIDCD NIH HHS F30 DC019510NIDCD NIH HHS F30-DC019510NIDCD NIH HHS F31 DC020129NIGMS NIH HHS T32 GM007347NIGMS NIH HHS T32-GM007347NIGMS NIH HHS T32 GM152284NIMH NIH HHS R01 MH102272
6 · The paper itself

Abstract

Interoception, the body's perception of its own internal states, is thought to be altered in autism, though results of empirical studies have been inconsistent. The current study systematically reviewed and meta-analyzed the extant literature comparing interoceptive outcomes between autistic (AUT) and neurotypical (NT) individuals, determining which domains of interoception demonstrate robust between-group differences. A three-level Bayesian meta-analysis compared heartbeat counting performance, heartbeat discrimination performance, heartbeat counting confidence ratings, and self-reported interoceptive attention between AUT and NT groups (15 studies; n

Indexed as

Autism Spectrum DisorderAutistic DisorderInteroceptionAttentionAwarenessBayes TheoremCase-Control StudiesHeart RateHumansAccuracyAttentionAutismInteroceptionMeta-analysisSensory

Identifiers

PMID35819587
PMCPMC9832174

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.