Evidence map›Paper›PMID 35819574›Full record

ArticleNeuroscience bulletin2022

Histones of Neutrophil Extracellular Traps Induce CD11b Expression in Brain Pericytes Via Dectin-1 after Traumatic Brain Injury.

Yang-Wuyue Liu, Jingyu Zhang, Wanda Bi, Mi Zhou, Jiabo Li, Tiantian Xiong, Nan Yang, Li Zhao, Xing Chen, Yuanguo Zhou and 5 more

Open access · greenAbstract read
In one paragraph

Article in Neuroscience bulletin, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Yang-Wuyue Liu *Department of Biochemistry and Molecular Biology, School of Basic Medicine, Army Medical University, Chongqing, 400038, China.
Jingyu Zhang *Department of Neurosurgery, Daping Hospital, Army Medical University, Chongqing, 400042, China.
Wanda Bi *Department of Biochemistry and Molecular Biology, School of Basic Medicine, Army Medical University, Chongqing, 400038, China.
Mi Zhou *Department of Biochemistry and Molecular Biology, School of Basic Medicine, Army Medical University, Chongqing, 400038, China.
Jiabo LiDepartment of Biochemistry and Molecular Biology, School of Basic Medicine, Army Medical University, Chongqing, 400038, China.
Tiantian XiongDepartment of Biochemistry and Molecular Biology, School of Basic Medicine, Army Medical University, Chongqing, 400038, China.
Nan YangMolecular Biology Center, State Key Laboratory of Trauma, Burn, and Combined Injury, Daping Hospital, Army Medical University, Chongqing, 400042, China.
Li ZhaoDepartment of Pathophysiology, College of High Altitude Medicine, Army Medical University, Chongqing, 400038, China.
Xing ChenMolecular Biology Center, State Key Laboratory of Trauma, Burn, and Combined Injury, Daping Hospital, Army Medical University, Chongqing, 400042, China.
Yuanguo ZhouMolecular Biology Center, State Key Laboratory of Trauma, Burn, and Combined Injury, Daping Hospital, Army Medical University, Chongqing, 400042, China.
Wenhui HeDepartment of Biochemistry and Molecular Biology, School of Basic Medicine, Army Medical University, Chongqing, 400038, China.
Teng YangDepartment of Biochemistry and Molecular Biology, School of Basic Medicine, Army Medical University, Chongqing, 400038, China.
Hao WangDepartment of Neurosurgery, Daping Hospital, Army Medical University, Chongqing, 400042, China. wanghaofz@sohu.com.
Lunshan XuDepartment of Neurosurgery, Daping Hospital, Army Medical University, Chongqing, 400042, China. asmczjy@yeah.net.
Shuang-Shuang DaiDepartment of Biochemistry and Molecular Biology, School of Basic Medicine, Army Medical University, Chongqing, 400038, China. tmmubiodss66@aliyun.com.
Army Medical University · CNDaping Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The brain pericyte is a unique and indispensable part of the blood-brain barrier (BBB), and contributes to several pathological processes in traumatic brain injury (TBI). However, the cellular and molecular mechanisms by which pericytes are regulated in the damaged brain are largely unknown. Here, we show that the formation of neutrophil extracellular traps (NETs) induces the appearance of CD11b

Indexed as

Brain Injuries, TraumaticExtracellular TrapsBlood-Brain BarrierBrainDectin-1HistonesHumansLectins, C-TypePericytesDectin-1HistonesLectins, C-TypeDectin-1NETNeutrophilPericyteTBI

Identifiers

PMID35819574
PMCPMC9554061
OpenAlexW4285025887

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.