Evidence map›Paper›PMID 35819477›Full record

ArticleClinical neuroradiology2023

The pCONUS2 and pCONUS2 HPC Neck Bridging Devices : Results from an International Multicenter Retrospective Study.

L Morales-Caba, I Lylyk, V Vázquez-Añón, C Bleise, E Scrivano, N Perez, P N Lylyk, J Lundquist, P Bhogal, P Lylyk

Full text readMulticenter Study
In one paragraph

Article in Clinical neuroradiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. pCONUS 2 and pCONUS 2-HPC in the treatment of wide-necked intracranial aneurysms: Multicentre UK experience.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

L Morales-CabaDepartment of Neuroradiology, Hospital Universitari i Politècnic La Fe, València, Spain.
I LylykClinica Sagrada Familia, ENERI, Buenos Aires, Argentina.
V Vázquez-AñónDepartment of Neuroradiology, Hospital Universitari i Politècnic La Fe, València, Spain.
C BleiseClinica Sagrada Familia, ENERI, Buenos Aires, Argentina.
E ScrivanoClinica Sagrada Familia, ENERI, Buenos Aires, Argentina.
N PerezClinica Sagrada Familia, ENERI, Buenos Aires, Argentina.
P N LylykClinica Sagrada Familia, ENERI, Buenos Aires, Argentina.
J LundquistClinica Sagrada Familia, ENERI, Buenos Aires, Argentina.
P BhogalDepartment of Interventional Neuroradiology, The Royal London Hospital, Barts NHS Trust, Whitechapel Road, E1 1BB, London, UK. bhogalweb@aol.com.ORCID http://orcid.org/0000-0002-5514-5237
P LylykClinica Sagrada Familia, ENERI, Buenos Aires, Argentina.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionBifurcation aneurysms represent an ongoing endovascular challenge with a variety of techniques and devices designed to address them. We present our multicenter series of the pCONUS2 and pCONUS2 HPC devices when treating bifurcation aneurysms.

methodsWe performed a retrospective review of our prospectively maintained databases at 3 tertiary neurointerventional centers to identify all patients who underwent coil embolization with the pCONUS2 or pCONUS2 HPC device between February 2015 and August 2021. We recorded baseline demographics, aneurysm data, complications, immediate and delayed angiographic results.

resultsWe identified 55 patients with 56 aneurysms, median age 63 years (range 42-78 years), 67.3% female (n = 37). The commonest aneurysm location was the MCA bifurcation (n = 40, 71.4%). Average dome height was 8.9 ± 4.2 mm (range 3.2-21.5 mm), average neck width 6.4 ± 2.5 mm (range 2.6-14 mm), and average aspect ratio 1.3 ± 0.6 (range 0.5-3.3). The pCONUS2 was used in 64.3% and the pCONUS2 HPC in 35.7%. The procedural technical success rate was 98.2%. Intraoperative complications occurred in 5 cases (8.9%), 4 of which were related to the coils with partial thrombus formation on the pCONUS2 HPC seen in 1 case that was resolved with heparin. In relation to the procedure and treatment of the aneurysm the overall permanent morbidity was 1.8% (n = 1/55) and mortality 0%. Delayed angiographic follow-up (48 aneurysms) at median 12 months postprocedure (range 3-36 months) demonstrated adequate occlusion of 83.4% of aneurysms.

conclusionThe pCONUS2 and pCONUS2 HPC devices carry a high technical success rate, low complication and retreatment rate, and good rates of adequate occlusion. Larger prospective confirmatory studies are required.

Indexed as

Embolization, TherapeuticEndovascular ProceduresIntracranial AneurysmAdultAgedFemaleHumansMaleMiddle AgedProspective StudiesRetreatmentRetrospective StudiesStentsTreatment OutcomeAneurysmBifurcation aneurysmPCONUS 2PCONUS2 HPCWide neck

Identifiers

PMID35819477
PMCPMC10014770

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Textfull text, public
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.