Evidence map›Paper›PMID 35819463›Full record

ArticleKnee surgery, sports traumatology, arthroscopy : official journal of the ESSKA2022

Arithmetic hip-knee-ankle angle and stressed hip-knee-ankle angle: equivalent methods for estimating constitutional lower limb alignment in kinematically aligned total knee arthroplasty.

Payam Tarassoli, Jil A Wood, Darren B Chen, Will Griffiths-Jones, Johan Bellemans, Samuel J MacDessi

Registry-linked trialAbstract read
In one paragraph

Article in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07410429 (Realigning Rehab), which is not on this map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07410429 naactive not recruitingnot on this mapstarted 2025, after this paper: background citation

Realigning Rehab: A Randomized Controlled Trial on Specific Exercises Versus Standard Care for Medial Knee Pain and Varus Alignment

TypeinterventionalSponsorAssiut UniversityRan2025 to 2026Enrolled80ConditionsKnee Osteoarthritis (Kellgren-Lawrence Grade 1-3)ArmsConventional Knee Physical Therapy Program, Targeted Alignment-Focused Exercise Program for Varus Knee
3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Payam TarassoliSydney Knee Specialists, Suite 201, Level 2, 131 Princes Hwy, Kogarah, NSW, 2217, Australia.
Jil A WoodSydney Knee Specialists, Suite 201, Level 2, 131 Princes Hwy, Kogarah, NSW, 2217, Australia.
Darren B ChenCPAK Research Group, Sydney, Australia.
Will Griffiths-JonesCPAK Research Group, Sydney, Australia.
Johan BellemansCPAK Research Group, Sydney, Australia.
Samuel J MacDessiCPAK Research Group, Sydney, Australia. samuelmacdessi@sydneyknee.com.au.ORCID http://orcid.org/0000-0002-1578-7614

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeKinematically aligned total knee arthroplasty (KA TKA) relies on precise determination of constitutional alignment to set resection targets. The arithmetic hip-knee-ankle angle (aHKA) is a radiographic method to estimate constitutional alignment following onset of arthritis. Intraoperatively, constitutional alignment may also be approximated using navigation-based angular measurements of deformity correction, termed the stressed HKA (sHKA). This study aimed to investigate the relationship between these methods of estimating constitutional alignment to better understand their utility in KA TKA.

methodsA radiological and intraoperative computer-assisted navigation study was undertaken comparing measurements of the aHKA using radiographs and computed tomography (CT-aHKA) to the sHKA in 88 TKAs meeting the inclusion criteria. The primary outcome was the difference in the paired means between the three methods to determine constitutional alignment (aHKA, CT-aHKA, sHKA). Secondary outcomes included testing agreement across measurements using Bland-Altman plots and analysis of subgroup differences based on different patterns of compartmental arthritis.

resultsThere were no statistically significant differences between any paired comparison or across groups (aHKA vs. sHKA: 0.1°, p = 0.817; aHKA vs. CT-aHKA: 0.3°, p = 0.643; CT-aHKA vs. sHKA: 0.2°, p = 0.722; ANOVA, p = 0.845). Bland-Altman plots were consistent with good agreement for all comparisons, with approximately 95% of values within limits of agreement. There was no difference in the three paired comparisons (aHKA, CT-aHKA, and sHKA) for knees with medial compartment arthritis. However, these findings were not replicated in knees with lateral compartment arthritis.

conclusionsThere was no significant difference between the arithmetic HKA (whether obtained using CT or radiographs) and the stressed HKA in this analysis. These findings further validate the preoperative arithmetic method and support use of the intraoperative stressed HKA as techniques to restore constitutional lower limb alignment in KA TKA. LEVEL OF EVIDENCE: III.

Indexed as

Arthroplasty, Replacement, KneeOsteoarthritis, KneeAnkleBiomechanical PhenomenaHumansKnee JointLower ExtremityRetrospective StudiesArithmetic HKAConstitutional alignmentKinematic alignmentStressed HKATotal knee arthroplasty

Identifiers

PMID35819463
PMCPMC9418303

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.