Evidence map›Paper›PMID 35819414›Full record

ArticleACS chemical biology2022

Spatiotemporal Proximity Labeling Tools to Track GlcNAc Sugar-Modified Functional Protein Hubs during Cellular Signaling.

Yimin Liu, Zachary M Nelson, Ali Reda, Charlie Fehl

Open access · greenAbstract read
In one paragraph

Article in ACS chemical biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Article
  6. O-GlcNAc informatics: advances and trends.Analytical and bioanalytical chemistry · 2025
    Review
  7. Article
  8. Article
  9. A Computational and Chemical Design Strategy for Manipulating Glycan-Protein Recognition.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  10. Article
  11. Tissue-specificeLife · 2024
    Article
  12. Article
  13. Review
  14. Proximity Labeling in Plants.Annual review of plant biology · 2023
    Review
  15. Cells · 2023
    Review
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Yimin LiuDepartment of Chemistry, Wayne State University, 5101 Cass Avenue, Detroit, Michigan 48202, United States.
Zachary M NelsonDepartment of Chemistry, Wayne State University, 5101 Cass Avenue, Detroit, Michigan 48202, United States.
Ali RedaDepartment of Chemistry, Wayne State University, 5101 Cass Avenue, Detroit, Michigan 48202, United States.
Charlie FehlDepartment of Chemistry, Wayne State University, 5101 Cass Avenue, Detroit, Michigan 48202, United States.ORCID 0000-0001-6182-0879
Wayne State University · US

Funding

Tumor Biology and Microenvironment (Program 1)P30CA022453 · NCI · WAYNE STATE UNIVERSITY · PI Julie Lynn Boerner · 1985 to 2026
$68.4M
THE ROLE OF CNS INSULIN AS A MODULATOR OF DIABETIC COMPLICATIONSR25GM058905 · NIGMS · WAYNE STATE UNIVERSITY · PI CHOW, CHRISTINE S, DUNBAR, JOSEPH C · 1999 to 2020
$14.4M
Spatiotemporal tools to interrogate O-GlcNAc functions in metabolic signaling and diseaseR35GM142637 · NIGMS · WAYNE STATE UNIVERSITY · PI Charlie Fehl · 2021 to 2026
$2.6M
Training Modules at Wayne State University to Promote Safe and Inclusive EnvironmentsT32GM139807 · NIGMS · WAYNE STATE UNIVERSITY · PI BRYANT-FRIEDRICH, AMANDA C, CHOW, CHRISTINE S · 2021 to 2025
$2.6M
NCI NIH HHS P30 CA022453NIGMS NIH HHS R25 GM058905NIGMS NIH HHS R35 GM142637NIGMS NIH HHS T32 GM139807
6 · The paper itself

Abstract

A fundamental mechanism that all eukaryotic cells use to adapt to their environment is dynamic protein modification with monosaccharide sugars. In humans, O-linked

Indexed as

ProteomicsSugarsAcetylglucosamineHumansInsulinProtein Processing, Post-TranslationalProteinsAcetylglucosamineInsulinProteinsSugars

Identifiers

PMID35819414
PMCPMC9391317
OpenAlexW4285077453

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.