Evidence map›Paper›PMID 35819393›Full record

ArticleJournal of law and medicine2022

Legal Implications of Stroke Biobanking and Genomics Research in Sub-Saharan Africa.

Muyiwa Adigun, Babatunde Raphael Ojebuyi, Joshua Akinyemi, Kolawole Wahab, Albert Akpalu, Fred S Sarfo, Lukman F Owolabi, Rabiu Musbahu, Abiodun Bello, Reginald Obiako and 10 more

Open access · greenAbstract read
In one paragraph

Article in Journal of law and medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 4 institutions in 3 countries.

Muyiwa AdigunDepartment of Public Law, University of Ibadan, Nigeria.
Babatunde Raphael OjebuyiDepartment of Communication and Language Arts, University of Ibadan.
Joshua AkinyemiNeurology Unit, University of Ilorin, Nigeria.
Kolawole WahabNeurology Unit, University of Ilorin, Nigeria.
Albert AkpaluUniversity of Ghana Medical School, Ghana.
Fred S SarfoNeurology Unit, Kwame Nkrumah University of Science and Technology, Ghana.
Lukman F OwolabiNeurology Unit, Bayero University, Nigeria.
Rabiu MusbahuNeurology Unit, Bayero University.
Abiodun BelloNeurology Unit, Department of Medicine, University of Ilorin.
Reginald ObiakoNeurology Unit, Ahmadu Bello University Teaching Hospital, Nigeria.
Mayowa OgunronbiNeuroscience and Ageing Research Unit, University of Ibadan.
Arti SinghSchool of Public Health, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Michelle NicholsCollege of Nursing, Medical University of South Carolina, United States.
Carolyn JenkinsCollege of Nursing, Medical University of South Carolina, United States.
Ayodele JegedeDepartment of Sociology, University of Ibadan.
Rajesh KalariaNeurovascular Research Group, Newcastle University, United Kingdom.
Mayowa OwolabiDepartment of Medicine, University of Ibadan.
Bruce OvbiageleWeill Institute of Neuroscience, University of California, San Franscisco, California, United States.
Oyedunni ArulogunDepartment of Health Promotion and Education, University of Ibadan.
Rufus AkinyemiNeuroscience and Ageing Research Unit, University of Ibadan.
University of Ibadan · NGMedical University of South Carolina · USKwame Nkrumah University of Science and Technology · GHUniversity of Ghana · GH

Funding

H3Africa Administrative Coordinating Centre: Enabling and Supporting Genomics and Health Research Capacity Building in AfricaU24HG009780 · NHGRI · UNIVERSITY OF CAPE TOWN · PI SKELTON, MICHELLE · 2017 to 2022
$4.8M
Stroke Investigative Research & Educational Network (SIREN)U54HG007479 · NHGRI · COLLEGE OF MEDICINE, UNIVERSITY OF IBADAN · PI OVBIAGELE, BRUCE, OWOLABI, MAYOWA OJO · 2013 to 2017
$4.2M
CNV And Stroke (CaNVAS)R01NS114045 · NINDS · UNIVERSITY OF MARYLAND BALTIMORE · PI COLE, JOHN W. · 2020 to 2024
$2.6M
African Rigorous Innovative Stroke Epidemiological Surveillance (ARISES)R01NS115944 · NINDS · COLLEGE OF MEDICINE, UNIVERSITY OF IBADAN · PI OVBIAGELE, BRUCE, OWOLABI, MAYOWA OJO · 2020 to 2025
$2.2M
Systematic Investigation of Blacks with Stroke - Genomics (SIBS-Genomics) StudyR01NS107900 · NINDS · COLLEGE OF MEDICINE, UNIVERSITY OF IBADAN · PI OVBIAGELE, BRUCE, OWOLABI, MAYOWA OJO · 2018 to 2021
$1.8M
Training Africans to Lead and Execute Neurological Trials & Studies (TALENTS)D43TW012030 · FIC · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI OVBIAGELE, BRUCE · 2021 to 2025
$1.2M
African Neurobiobank for Precision Stroke Medicine - (ELSI) ProjectU01HG010273 · NHGRI · COLLEGE OF MEDICINE, UNIVERSITY OF IBADAN · PI AKINYEMI, RUFUS OLUSOLA, ARULOGUN, OYEDUNNI SOLA · 2018 to 2022
$512k
Sub-Saharan Africa Conference on Stroke (SSACS) ConferenceR13NS115395 · NINDS · NORTHERN CALIFORNIA INSTITUTE/RES/EDU · PI OVBIAGELE, BRUCE · 2020 to 2020
$50k
FIC NIH HHS D43 TW012030NHGRI NIH HHS U01 HG010273NHGRI NIH HHS U24 HG009780NHGRI NIH HHS U54 HG007479NINDS NIH HHS R01 NS107900NINDS NIH HHS R01 NS114045NINDS NIH HHS R01 NS115944NINDS NIH HHS R13 NS115395
6 · The paper itself

Abstract

Stroke is a major cause of death in Sub-Saharan Africa (SSA) and genetic factors appear to play a part. This has led to stroke biobanking and genomics research in SSA. Existing stroke studies have focused on causes, incidence rates, fatalities and effects. However, scant attention has been paid to the legal issues in stroke biobanking and genomics research in the sub-region. Therefore, this article examines the legal implications of stroke biobanking and genomics research in SSA. The article adopts a textual analysis of primary and secondary sources in law. It reports that there are laws from the perspectives of human right, the common law, and intellectual property. However, there are gaps to be filled. The article therefore argues for legislative intervention. It concludes that pending the time the statute will be enacted, genomics researchers in Africa should adopt the ethical guidelines prepared by Human Heredity and Health in Africa (H3 Africa).

Indexed as

Biological Specimen BanksStrokeAfrica South of the SaharaGenomicsHumansbioethicsgene editing germ cell editinggenetic engineeringscientific regulation

Identifiers

PMID35819393
PMCPMC11328967
OpenAlexW4285078621

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.