ArticleeLife2022
BK channel properties correlate with neurobehavioral severity in three
Open access · goldAbstract read
In one paragraph
Article in eLife, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.8field-weighted citation impact, top 8% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 34 citations in OpenAlex.
- Fibronectin1-Expressing Subicular Circuits Selectively Govern the Retrieval of Novel Object Recognition.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Case report: Whole-exome sequencing reveals a novel variant in a patient with epilepsy presenting with fever.Frontiers in genetics · 2026Article
- Magnesium Ions as Modulators of Voltage-Gated and Ligand-Gated Ion Channels in Central Neurons.International journal of molecular sciences · 2025Review
- BK channel activity in skin fibroblasts from patients with neurological disorder.Channels (Austin, Tex.) · 2025Article
- Article
- Circadian Control of Sleep by Melatonin via MTbioRxiv : the preprint server for biology · 2025Article
- The NMDAR-BK channelosomes as regulators of synaptic plasticity.Biochemical Society transactions · 2025Review
- Characterizing molecular and behavioral changes arising from ROMK potassium channel deficiency in the cerebellum.Frontiers in behavioral neuroscience · 2025Article
- Altered trial-to-trial responses to reward outcomes in KCNMA1 knockout mice during probabilistic learning tasks.Behavioral and brain functions : BBF · 2024Article
- Evaluation of fourChannels (Austin, Tex.) · 2024Article
- Phenotype remodelling of HNSCC cells in the muscle invasion environment.Journal of translational medicine · 2024Article
- Transmembrane determinants of voltage-gating differences between BK (Slo1) and Slo3 channels.Biophysical journal · 2024Article
- Structural mapping of patient-associated KCNMA1 gene variants.Biophysical journal · 2024Article
- Large conductance voltage-and calcium-activated KFrontiers in pharmacology · 2024Review
- Disease-associated KCNMA1 variants decrease circadian clock robustness in channelopathy mouse models.The Journal of general physiology · 2023Article
- Incorporating physics to overcome data scarcity in predictive modeling of protein function: A case study of BK channels.PLoS computational biology · 2023Article
- Unveiling the impact of lysosomal ion channels: balancing ion signaling and disease pathogenesis.The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2023Review
- Incorporating physics to overcome data scarcity in predictive modeling of protein function: a case study of BK channels.bioRxiv : the preprint server for biology · 2023Article
- BK channel modulation by positively charged peptides and auxiliary γ subunits mediated by the Ca2+-bowl site.The Journal of general physiology · 2023Article
- BK channels of five different subunit combinations underlie the de novo KCNMA1 G375R channelopathy.The Journal of general physiology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 1 institution in 1 country.
Su Mi ParkDepartment of Physiology, University of Maryland School of Medicine, Baltimore, United States.
Cooper E RoacheDepartment of Physiology, University of Maryland School of Medicine, Baltimore, United States.
Philip H IfflandDepartment of Neurology, University of Maryland School of Medicine, Baltimore, United States.
Hans J MoldenhauerDepartment of Physiology, University of Maryland School of Medicine, Baltimore, United States.
Katia K MatychakDepartment of Physiology, University of Maryland School of Medicine, Baltimore, United States.ORCID 0000-0001-5094-5449
Amber E PlanteDepartment of Physiology, University of Maryland School of Medicine, Baltimore, United States.
Abby G LiebermanDepartment of Pharmacology, University of Maryland School of Medicine, Baltimore, United States.
Peter B CrinoDepartment of Neurology, University of Maryland School of Medicine, Baltimore, United States.
Andrea MeredithDepartment of Physiology, University of Maryland School of Medicine, Baltimore, United States.ORCID 0000-0003-1061-2302
University of Maryland, Baltimore · US
Funding
QAQC Johns Hopkins Institute for Clinical and Translational ResearchUL1TR003098 · NCATS · JOHNS HOPKINS UNIVERSITY · PI FORD, DANIEL ERNEST · 2019 to 2023
$57.7MInterdisciplinary Training Program Muscle BiologyT32AR007592 · NIAMS · UNIVERSITY OF MARYLAND BALTIMORE · PI Aikaterini Kontrogianni-Konstantopoulos · 1996 to 2026
$11.7MDaily Regulation of Ionic CurrentsR01HL102758 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI LEDERER, WILLIAM JONATHAN · 2010 to 2024
$6.3MTRAINING PROGRAM IN INTEGRATIVE MEMBRANE BIOLOGYT32GM008181 · NIGMS · UNIVERSITY OF MARYLAND BALTIMORE · PI RIZZO, MEGAN A, TRUDEAU, MATTHEW C · 1987 to 2022
$4.9MSomatic Mutation in Intractable Focal EpilepsyR01NS114122 · NINDS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI CRINO, PETER B, HEINZEN, ERIN L · 2020 to 2024
$3.3MNCATS NIH HHS UL1 TR003098NHLBI NIH HHS R01 HL102758NIAMS NIH HHS T32 AR007592NIGMS NIH HHS T32 GM008181NINDS NIH HHS R01 NS114122
Abstract
KCNMA1 forms the pore of BK K
Indexed as
ChannelopathiesLarge-Conductance Calcium-Activated Potassium Channel alpha SubunitsAnimalsChoreaDisease Models, AnimalEpilepsy, GeneralizedMiceMice, TransgenicSeizuresKcnma1 protein, mouseLarge-Conductance Calcium-Activated Potassium Channel alpha SubunitsBK channelcalcium-activated potassium channeldentate gyrusepilepsyKCNMA1mouseneuroscienceparoxysmal non-kinesigenic dyskinesia
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.