Evidence map›Paper›PMID 35819098›Full record

ReviewOrthopaedic surgery2022

Catastrophic Periprosthetic Osteolysis in Total Hip Arthroplasty at 20 Years: A Case Report and Literature Review.

Dan Xing, Rujun Li, Jiao Jiao Li, Ke Tao, Jianhao Lin, Taiqiang Yan, Diange Zhou

Open access · goldAbstract readCase ReportsReview
In one paragraph

Review in Orthopaedic surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Frontiers in bioengineering and biotechnology · 2025
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Dan XingArthritis Clinic & Research Center, Peking University People's Hospital, Peking University, Beijing, China.ORCID https://orcid.org/0000-0001-6966-3134
Rujun LiArthritis Clinic & Research Center, Peking University People's Hospital, Peking University, Beijing, China.
Jiao Jiao LiSchool of Biomedical Engineering, Faculty of Engineering and IT, University of Technology Sydney, Ultimo, Australia.
Ke TaoArthritis Clinic & Research Center, Peking University People's Hospital, Peking University, Beijing, China.
Jianhao LinArthritis Clinic & Research Center, Peking University People's Hospital, Peking University, Beijing, China.ORCID https://orcid.org/0000-0003-1830-9244
Taiqiang YanMusculoskeletal Tumor Center, Peking University People's Hospital, Peking University, Beijing, China.
Diange ZhouArthritis Clinic & Research Center, Peking University People's Hospital, Peking University, Beijing, China.
Peking University · CNUniversity of Technology Sydney · AU

Funding

National Natural Science Foundation of China 81501919Peking University People's Hospital RXD2020-02
6 · The paper itself

Abstract

backgroundPeriprosthetic osteolysis is a serious complication following total hip arthroplasty (THA). However, most orthopedic surgeons only focus on bone loss and hip reconstruction. Thus, it was required to understand the treatment algorithm for periprosthetic osteolysis integrally. CASE PRESENTATION: A 52-year-old Asian male presented with chronic hip pain. A mass appeared on the medial side of the proximal left thigh at more than 20 years after bilateral THA. Radiographs revealed catastrophic periprosthetic osteolysis, especially on the acetabular side. Large amounts of necrotic tissue and bloody fluids were thoroughly debrided during revision THA. A modular hemipelvic prosthesis was used for revision of the left hip. Four years later, the patient presented with right hip pain, where a mass appeared on the medial side of the proximal right thigh. A primary acetabular implant with augment was used for revision of the right hip. Laboratory evaluation of bloody fluid retrieved from surgery revealed elevated levels of inflammatory markers.

conclusionInflammatory responses to polyethylene wear debris can lead to severe bone resorption and aseptic loosening in the long-term following THA. Therefore, in spite of revision THA, interrupting the cascade inflammatory might be the treatment principle for periprosthetic osteolysis.

Indexed as

Arthroplasty, Replacement, HipHip ProsthesisOsteolysisHumansMaleMiddle AgedPainProsthesis DesignProsthesis FailureReoperationInflammationPeriprosthetic osteolysisPolyethylene wearRevision surgeryTotal hip arthroplasty

Identifiers

PMID35819098
PMCPMC9363776
OpenAlexW4285040847

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.