Evidence map›Paper›PMID 35819034›Full record

ReviewJournal of medical virology2022

SARS-CoV-2 infection and lytic reactivation of herpesviruses: A potential threat in the postpandemic era?

Jungang Chen, Jiao Song, Lu Dai, Steven R Post, Zhiqiang Qin

Open access · greenAbstract readReview
In one paragraph

Review in Journal of medical virology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
7.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 34 citations in OpenAlex.

  1. The Current Status ofPathogens (Basel, Switzerland) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jungang ChenDepartment of Pathology, Winthrop P. Rockefeller Cancer Institute, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Jiao SongDepartment of Pathology, Winthrop P. Rockefeller Cancer Institute, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Lu DaiDepartment of Pathology, Winthrop P. Rockefeller Cancer Institute, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Steven R PostDepartment of Pathology, Winthrop P. Rockefeller Cancer Institute, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Zhiqiang QinDepartment of Pathology, Winthrop P. Rockefeller Cancer Institute, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.ORCID 0000-0002-9905-1275
Winthrop Rockefeller Foundation · US

Funding

Periodontal bacteria enhance oral KSHV pathogenesis and Kaposi’s Sarcoma development in HIV+ patientsR01CA228166 · NCI · UNIV OF ARKANSAS FOR MED SCIS · PI FORREST, JAMES CRAIG, POST, STEVEN · 2018 to 2023
$1.9M
Targeting ILlRAP in virus-associated malignanciesR03DE031978 · NIDCR · UNIV OF ARKANSAS FOR MED SCIS · PI DAI, LU · 2022 to 2023
$304k
NCI NIH HHS R01 CA228166NIDCR NIH HHS R03 DE031978NIH HHS
6 · The paper itself

Abstract

The outbreak of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is the causative pathogen for the coronavirus disease 2019 (COVID-19) pandemic, has greatly stressed our healthcare system. In addition to severe respiratory and systematic symptoms, several comorbidities increase the risk of fatal disease outcomes, including chronic viral infections. Increasing cases of lytic reactivation of human herpesviruses in COVID-19 patients and vaccinated people have been reported recently. SARS-CoV2 coinfection, COVID-19 treatments, and vaccination may aggravate those herpesvirus-associated diseases by reactivating the viruses in latently infected host cells. In this review, we summarize recent clinical findings and limited mechanistic studies regarding the relationship between SARS-CoV-2 and different human herpesviruses that suggest an ongoing potential threat to human health in the postpandemic era.

Indexed as

COVID-19HerpesviridaeHumansPandemicsRNA, ViralSARS-CoV-2RNA, ViralCOVID-19herpesviruslyticpandemicSARS-CoV-2

Identifiers

PMID35819034
PMCPMC9350099
OpenAlexW4285077215

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.