Evidence map›Paper›PMID 35818709›Full record

ArticleAmerican journal of rhinology & allergy2022

Clinical and Quality of Life Outcomes Following Temperature-Controlled Radiofrequency Neurolysis of the Posterior Nasal Nerve (RhinAer) for Treatment of Chronic Rhinitis.

Jivianne T Lee, Gregory M Abbas, Daniel D Charous, Pd Dr Med Mandy Cuevas, Prof Dr Med Önder Göktas, Patricia A Loftus, Nathan E Nachlas, Elina M Toskala, Jeremy P Watkins, Prof Dr Med Detlef Brehmer

3 registry-linked trialsOpen access · hybridAbstract readMulticenter Study
In one paragraph

Article in American journal of rhinology & allergy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04614324 nacompletednot on this map

A Prospective, Open Label, Multi-Center Study Using the RhinAer Procedure for Treatment of Subjects Suffering With Chronic Rhinitis

TypeinterventionalSponsorAerin MedicalRan2020 to 2024Enrolled129ConditionsChronic RhinitisArmsRhinAer ARC Stylus
NCT07050992 naactive not recruitingnot on this mapstarted 2024, after this paper: background citation

Laser Posterior Nasal Nerve Neurolysis: a Randonmized Controlled Trial

TypeinterventionalSponsorChiayi Christian HospitalRan2024 to 2026Enrolled120ConditionsAllergic Rhinitis, Chronic Rhinitis, Rhinorrhea, SneezingArmsLaser posterior nasal nerve neurolysis, Sham surgery
NCT07323888 naactive not recruitingnot on this mapstarted 2026, after this paper: background citation

Comparison of Traditional Radiofrequency Ablation of Inferior Turbinates With or Without Posterior Nasal Radiofrequency Ablation: A Randomized Controlled Trial

TypeinterventionalSponsorChien Yu HuangRan2026 to 2027Enrolled60ConditionsNasal Obstruction, Chronic Rhinitis, Nonallergic Rhinitis, RhinorrheaArmsTraditional Radiofrequency Ablation of Inferior Turbinates With Posterior Nasal Radiofrequency Ablation, Traditional Radiofrequency Ablation of Inferior Turbinates
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Effectiveness of temperature-controlled radiofrequency neurolysis of the posterior nasal nerve to treat chronic rhinitis: a systematic review and meta-analysis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024
    Pooled it
  2. Trial
  3. Trial
  4. Radiofrequency Ablation Versus Laser Neurolysis of the Posterior Nasal Nerve in Patients With Chronic Rhinitis.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2026
    Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 8 institutions in 2 countries.

Jivianne T LeeDepartment of Head and Neck Surgery, UCLA David Geffen School of Medicine, Los Angeles, CA, USA.ORCID 0000-0002-0711-855X
Gregory M AbbasAdvanced ENT and Allergy, Louisville, KY, USA.
Daniel D CharousArizona Desert Ear, Nose & Throat Specialists, Goodyear, AZ, USA.
Pd Dr Med Mandy CuevasDepartment of Otorhinolaryngology, University Clinic Carl Gustav Carus, Technical University of Dresden, Dresden, Germany.
Prof Dr Med Önder GöktasENT-Center, HNO-Zentrum am Kudamm, Berlin, Germany.
Patricia A LoftusDepartment of Otolaryngology-Head and Neck Surgery, University of California, San Francisco, San Francisco, CA, USA.
Nathan E NachlasENT and Allergy Associates of Florida, Boca Raton, FL, USA.
Elina M ToskalaDepartment of Otolaryngology - Head & Neck Surgery, Thomas Jefferson University, Philadelphia, PA, USA.
Jeremy P WatkinsFort Worth ENT Group, Fort Worth, TX, USA.
Prof Dr Med Detlef BrehmerFaculty of Medicine, University Witten/Herdecke, Witten, Germany.
Advanced ENT and Allergy · USENT and Allergy Associates of Florida · USGoodyear (United States) · USThomas Jefferson University · USUniversity Hospital Carl Gustav Carus · DEUniversity of California, Los Angeles · USUniversity of California, San Francisco · USWitten/Herdecke University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTemperature-controlled radiofrequency (TCRF) neurolysis of the posterior nasal nerve (PNN; RhinAer) is a minimally invasive treatment option for patients with chronic rhinitis.

objectiveTo determine clinical outcomes and quality of life (QoL) following TCRF neurolysis of the PNN.

methodsA prospective single-arm study of 129 patients with chronic rhinitis at 16 medical centers in the United States and Germany.

resultsThe mean 24-h reflective total nasal symptom score (rTNSS) improved from 7.8 (95% CI, 7.5-8.1) at baseline to 3.6 (95% CI, 3.2-4.0) at 3 months and continued to improve to 2.9 (95% CI, 2.5-3.3) at 6 months (

conclusionIn this large, multicenter study, TCRF neurolysis of the PNN was safe and resulted in a significant reduction in rhinitis symptom burden at 3 months that was sustained/improved through 6 months. The majority of patients reported a clinically relevant improvement in QoL at 3 and 6 months postprocedure.

Indexed as

RhinitisHumansProspective StudiesQuality of LifeSurveys and QuestionnairesTemperatureTreatment Outcomechronic rhinitisMiniRQLQneurolysisposterior nasal nervequality of liferadiofrequencyrTNSStemperature-controlled

Identifiers

PMID35818709
PMCPMC9548948
OpenAlexW4285077518

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.