Evidence map›Paper›PMID 35818703›Full record

ArticleJournal of Korean medical science2022

Cost-Benefit Analysis of Tafenoquine for Radical Cure of

Jiyeon Suh, Jung Ho Kim, Jong-Dae Kim, Changsoo Kim, Jun Yong Choi, Jeehyun Lee, Joon-Sup Yeom

Open access · goldAbstract read
In one paragraph

Article in Journal of Korean medical science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Development of aFrontiers in public health · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Jiyeon Suh *School of Mathematics and Computing (Computational Science and Engineering), Yonsei University, Seoul, Korea.ORCID https://orcid.org/0000-0001-8597-5488
Jung Ho Kim *Department of Internal Medicine and AIDS Research Institute, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-5033-3482
Jong-Dae KimDepartment of General Surgery, Bestian Woosong Hospital, Daejeon, Korea.ORCID https://orcid.org/0000-0002-4424-9399
Changsoo KimDepartment of Preventive Medicine, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-5940-5649
Jun Yong ChoiDepartment of Internal Medicine and AIDS Research Institute, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-2775-3315
Jeehyun LeeSchool of Mathematics and Computing, Yonsei University, Seoul, Korea. ezhyun@yonsei.ac.kr.ORCID https://orcid.org/0000-0001-6143-2294
Joon-Sup YeomDepartment of Internal Medicine and AIDS Research Institute, Yonsei University College of Medicine, Seoul, Korea. joonsup.yeom@yuhs.ac.ORCID https://orcid.org/0000-0001-8940-7170
Yonsei University · KR

Funding

Government-wide R&D Fund GFID-HG20C0003National Research Foundation of Korea NRF-2020R1A2C1A01010775
6 · The paper itself

Abstract

background

methodsWe expanded the previously developed

resultsUnder 0.04 primaquine relapse probability, the introduction of tafenoquine with relapse probability of 0.01 prevented 129 (12.27%) and 35 (77.78%) total and relapse cases, respectively, over the next decade. However, under the same relapse probability as primaquine, introducing tafenoquine had no additional preventative effect. The 14-day primaquine treatment cost was $3.71. The tafenoquine and the glucose-6-phosphate dehydrogenase rapid diagnostic testing cost $57.37 and $7.76, totaling $65.13. The average medical expenditure per malaria patient was estimated at $1444.79. The cost-benefit analysis results provided an incremental benefit-cost ratio (IBCR) from 0 to 3.21 as the tafenoquine relapse probability decreased from 0.04 to 0.01. The probabilistic sensitivity analysis showed an IBCR > 1, indicating that tafenoquine is beneficial, with a probability of 69.1%.

conclusionTafenoquine could reduce

Indexed as

AntimalarialsMalaria, VivaxAminoquinolinesCost-Benefit AnalysisHumansPrimaquineRecurrenceAminoquinolinesAntimalarialsPrimaquinetafenoquineCost-Benefit AnalysisMalariaModelingTafenoquine

Identifiers

PMID35818703
PMCPMC9274106
OpenAlexW4285077944

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.