Evidence map›Paper›PMID 35818397›Full record

ArticleNew microbes and new infections2022

First case of within-host co-infection of different SARS-CoV-2 variants in Ecuador.

J C Fernandez-Cadena, M Carvajal, E Muñoz, B Prado-Vivar, S Marquez, S Proaño, R Bayas, J J Guadalupe, M Becerra-Wong, B Gutierrez and 7 more

Abstract read
In one paragraph

Article in New microbes and new infections, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

J C Fernandez-CadenaLaboratorio INTERLAB, Ecuador.
M CarvajalUniversidad San Francisco de Quito, COCIBA, Instituto de Microbiología, Ecuador.
E MuñozUniversidad San Francisco de Quito, COCIBA, Instituto de Microbiología, Ecuador.
B Prado-VivarUniversidad San Francisco de Quito, COCIBA, Instituto de Microbiología, Ecuador.
S MarquezUniversidad San Francisco de Quito, COCIBA, Instituto de Microbiología, Ecuador.
S ProañoUniversidad San Francisco de Quito, COCIBA, Instituto de Microbiología, Ecuador.
R BayasUniversidad San Francisco de Quito, COCIBA, Instituto de Microbiología, Ecuador.
J J GuadalupeUniversidad San Francisco de Quito, COCIBA, Laboratorio de Biotecnología Vegetal, Ecuador.
M Becerra-WongUniversidad San Francisco de Quito, COCIBA, Instituto de Microbiología, Ecuador.
B GutierrezUniversidad San Francisco de Quito, COCIBA, Laboratorio de Biotecnología Vegetal, Ecuador.
G Morey-LeonUniversidad de Guayaquil, Ecuador.
G TruebaUniversidad San Francisco de Quito, COCIBA, Instituto de Microbiología, Ecuador.
M GrunauerUniversidad San Francisco de Quito, COCSA, Escuela de Medicina, Ecuador.
V BarragánUniversidad San Francisco de Quito, COCIBA, Instituto de Microbiología, Ecuador.
P Rojas-SilvaUniversidad San Francisco de Quito, COCIBA, Instituto de Microbiología, Ecuador.
D Andrade-MolinaUniversidad Espíritu Santo, Laboratorio de Omicas, Ecuador.
P CárdenasUniversidad San Francisco de Quito, COCIBA, Instituto de Microbiología, Ecuador.

Funding

T Cell Responses Following DENV Natural Infections and Live-Attenuated Dengue Virus VaccinationP01AI106695 · NIAID · UNIVERSITY OF CALIFORNIA BERKELEY · PI Aravinda M. DeSilva · 2015 to 2026
$34.1M
American Asian Centers for Arbovirus Research and Enhanced Surveillance (A2CARES)U01AI151788 · NIAID · UNIVERSITY OF CALIFORNIA BERKELEY · PI Josefina Coloma, Eva Harris · 2020 to 2026
$9.6M
NIAID NIH HHS U01 AI151788
6 · The paper itself

Abstract

Background: COVID-19 infection caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can cause mild symptoms to severe illness and death. Co-infections of SARS-CoV-2 with other respiratory viruses have been described. However, two SARS-CoV-2 lineage co-infection have been rarely reported. Methodology: A genotyping analysis and two different types of whole genome sequencing were performed (Illumina MiniSeq and ONT MinION). When examining the phylogenetic analysis in NextClade and Pangolin webservers, and considering the genotyping findings, conflicting results were obtained. Results: The raw data of the sequencing was analyzed, and nucleotide variants were identified between different reads of the virus genome. B.1 and P.1 lineages were identified within the same sample. Conclusions: We concluded that this is a co-infection case with two SARS-CoV-2 lineages, the first one reported in Ecuador.

Indexed as

co-infectionCOVID19genome sequencingNGSSARS-CoV-2

Identifiers

PMID35818397
PMCPMC9259011

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.