Evidence map›Paper›PMID 35818297›Full record

Observational studyJournal of radiation research2022

Abnormal sensation during total body irradiation: a prospective observational study.

Masashi Mizumoto, Yoshiko Oshiro, Toshio Miyamoto, Taisuke Sumiya, Shosei Shimizu, Takashi Iizumi, Takashi Saito, Hirokazu Makishima, Haruko Numajiri, Kei Nakai and 4 more

Abstract readObservational Study
In one paragraph

Observational study in Journal of radiation research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Abnormal visual and olfactory sensations during radiation therapy: a prospective study.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2023
    Article
  2. Synchronization of light flash with the irradiation pulse in proton beam therapy: A case report.Technical innovations & patient support in radiation oncology · 2023
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Masashi MizumotoDepartment of Radiation Oncology, University of Tsukuba, Tsukuba, Ibaraki 305-8576, Japan.
Yoshiko OshiroDepartment of Radiation Oncology, University of Tsukuba, Tsukuba, Ibaraki 305-8576, Japan.
Toshio MiyamotoDepartment of Radiation Oncology, University of Tsukuba, Tsukuba, Ibaraki 305-8576, Japan.
Taisuke SumiyaDepartment of Radiation Oncology, University of Tsukuba, Tsukuba, Ibaraki 305-8576, Japan.
Shosei ShimizuDepartment of Radiation Oncology, University of Tsukuba, Tsukuba, Ibaraki 305-8576, Japan.
Takashi IizumiDepartment of Radiation Oncology, University of Tsukuba, Tsukuba, Ibaraki 305-8576, Japan.
Takashi SaitoDepartment of Radiation Oncology, University of Tsukuba, Tsukuba, Ibaraki 305-8576, Japan.
Hirokazu MakishimaDepartment of Radiation Oncology, University of Tsukuba, Tsukuba, Ibaraki 305-8576, Japan.
Haruko NumajiriDepartment of Radiation Oncology, University of Tsukuba, Tsukuba, Ibaraki 305-8576, Japan.
Kei NakaiDepartment of Radiation Oncology, University of Tsukuba, Tsukuba, Ibaraki 305-8576, Japan.
Toshiyuki OkumuraDepartment of Radiation Oncology, University of Tsukuba, Tsukuba, Ibaraki 305-8576, Japan.
Takeji SakaeDepartment of Radiation Oncology, University of Tsukuba, Tsukuba, Ibaraki 305-8576, Japan.
Kazushi MaruoDepartment of Biostatistics, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki 305-8575, Japan.
Hideyuki SakuraiDepartment of Radiation Oncology, University of Tsukuba, Tsukuba, Ibaraki 305-8576, Japan.

Funding

University of Tsukuba
6 · The paper itself

Abstract

Light flash and odor during radiotherapy are well-known phenomena. Two prospective observational studies have indicated that 55% of patients observed a light flash during irradiation of the retina and 27% of patients sensed an odor during radiotherapy for the nasal cavity. A prospective observational study was performed in all patients at our hospital who received total body irradiation (TBI) between January 2019 to October 2021. Light flash and odor during TBI were examined using the same method as that used in previous studies. A total of 32 patients received TBI during the study period. The patients had a median age of 41 (18-60) years, and included 20 males and 12 females. A survey checklist showed that 14 patients (44%) sensed light and 14 patients (44%) sensed odor during TBI,. The color of the light during irradiation was yellow in six cases, white in four cases, and blue in four cases. The intensity of the light was 2-5 (median 3, 1 is very weak, 5 is very strong) and the time over which the light flash was felt was 4-60 s (median 10 s). Two patients each sensed smells of plastic, ozone and bleach, and others sensed one smell each. The intensity of the odor was 1-4 (median 3, 1 is very weak, 5 is very strong) and the time over which the odor was sensed was 1-25 s (median 3 s). We conclude that light flashes and odors are each sensed by 44% of patients during TBI. Various types of light flashes and odors were reported in this study.

Indexed as

OzoneWhole-Body IrradiationAdultFemaleHumansMaleMiddle AgedOdorantsPlasticsSmellOzonePlasticslight flashobservation studyodorprospectiveradiotherapytotal body irradiation (TBI)

Identifiers

PMID35818297
PMCPMC9494512

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.