Evidence map›Paper›PMID 35818159›Full record

Observational studyThe Journal of international medical research2022

Mannose-binding lectin 2 gene polymorphisms and predisposition to allergic bronchial asthma in a western Romanian children population: an observational study.

Simona Maria Borta, Imola Donath-Miklos, Romana Popetiu, Dragos Vasile Nica, Diana Nitusca, Adrian Crisan, Catalin Marian, Maria Puschita

Abstract readObservational Study
In one paragraph

Observational study in The Journal of international medical research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Simona Maria BortaDepartment of Internal Medicine, Faculty of Medicine, 'Vasile Goldis' Western University of Arad, Romania.ORCID https://orcid.org/0000-0002-2512-2691
Imola Donath-MiklosDepartment of Physiology, Faculty of Medicine, 'Vasile Goldis' Western University of Arad, Romania.
Romana PopetiuDepartment of Internal Medicine, Faculty of Medicine, 'Vasile Goldis' Western University of Arad, Romania.
Dragos Vasile NicaDepartment of Toxicology, Faculty of Pharmacy, 'Victor Babes' University of Medicine and Pharmacy Timisoara, Romania.
Diana NituscaDepartment of Biochemistry and Pharmacology, 'Victor Babes' University of Medicine and Pharmacy Timisoara, Romania.ORCID https://orcid.org/0000-0002-5325-5221
Adrian CrisanDepartment of Critical Care and Emergency Medicine, 'Vasile Goldis' Western University of Arad, Romania.
Catalin MarianDepartment of Biochemistry and Pharmacology, 'Victor Babes' University of Medicine and Pharmacy Timisoara, Romania.
Maria PuschitaDepartment of Internal Medicine, Faculty of Medicine, 'Vasile Goldis' Western University of Arad, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo analyse: (1) the associations between different mannose-binding lectin 2 (

methodsThis prospective observational case-control study included paediatric patients with symptomatic BA and healthy controls. Participants were genotyped for two

resultsAmong 59 patients with BA and 65 healthy controls, associations between

conclusionThese results may help guide future research into paediatric BA in Romania and Eastern Europe. Due to study limitations, the results require validation in future large-scale studies.

Indexed as

AsthmaMannose-Binding LectinCase-Control StudiesChildFemaleGenetic Predisposition to DiseaseGenotypeHumansMalePolymorphism, Single NucleotideRomaniaMannose-Binding LectinMBL2 protein, humanBronchial asthmachildrenMBL2polymorphismrs11003125rs1800450

Identifiers

PMID35818159
PMCPMC9280823

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.