ReviewParasites & vectors2022
Review and statistical analysis of clinical management of feline leishmaniosis caused by Leishmania infantum.
Review in Parasites & vectors, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 22 citations in OpenAlex.
- LeishVet update and current recommendations on feline leishmaniosis.Parasites & vectors · 2026Review
- Acute Phase Proteins in Cats Naturally Infected or Seropositive forAnimals : an open access journal from MDPI · 2026Article
- p1/s1, a 3'-nucleotidase/nuclease, allows Leishmania major to circumvent host innate immune response mechanisms.PLoS pathogens · 2026Article
- Diagnostic potential of a multi-antigen ELISA for feline leishmaniosis.Parasites & vectors · 2026Article
- Seroprevalence ofMicroorganisms · 2026Article
- Detection of circulating immune complexes in feline leishmaniosis: first evidence and diagnostic implications.Veterinary research communications · 2026Article
- Cytokine gene expression in feline leishmaniasis: why cats might be less clinically affected than dogs.Parasites & vectors · 2026Article
- Molecular and Serological Detection ofAnimals : an open access journal from MDPI · 2025Article
- Advancing diagnosis of feline Leishmania infantum infection through experimental insights.Scientific reports · 2025Article
- Emergence of autochthonousFrontiers in veterinary science · 2025Article
- Infectiousness to sand flies of a cat naturally infected with Leishmania infantum at the moment of diagnosis and after three different courses of treatment.Revista brasileira de parasitologia veterinaria = Brazilian journal of veterinary parasitology : Orgao Oficial do Colegio Brasileiro de Parasitologia Veterinaria · 2025Article
- Exploring Emerging Challenges: Survey on Phlebotomine Sand Flies andPathogens (Basel, Switzerland) · 2024Article
- Assessment of the exposure toThe veterinary quarterly · 2024Article
- Feline leishmaniosis in the Mediterranean Basin: a multicenter study.Parasites & vectors · 2024Article
- Article
- A case report of leishmaniosis with primary oral manifestation in a cat.Frontiers in veterinary science · 2022Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere is limited information about feline leishmaniosis (FeL) management in clinical practice. Leishmania infantum is the species of Leishmania most frequently reported in both dogs and cats in countries of the Mediterranean region (henceforth 'Mediterranean countries'), Central and South America, and Iran. This study was conducted to provide veterinary clinicians with an updated overview of evidence-based information on leishmaniosis in cats.
methodsA review was performed using PubMed, Science Direct, Google Scholar and Web of Science. Case reports of FeL caused by L. infantum were sought for the period 1912 to 1 June 2021.
resultsSixty-three case reports are included in this review. Fifty-nine out of the 63 cats were from Europe, mostly from Mediterranean countries (88.9%). Most of them were domestic short-haired cats (90%) with a mean age of 7.9 years, and had access to the outdoors (77.3%). Sixty-six percent of the cats had comorbidities, of which feline immunodeficiency virus infection was the most frequent (37.7%). Dermatological lesions (69.8%) was the most frequent clinical sign, and hyperproteinemia (46.3%) the most frequent clinicopathological abnormality. Serology was the most performed diagnostic method (76.2%) and was positive for 93.7% of cats. Medical treatment was applied in 71.4% of cats, and allopurinol was the most used drug (74.4%). Survival time was greater for treated cats (520 days; 71.4% of cats) than non-treated cats (210 days; 25.4%).
conclusionsThe majority of the cats had comorbidities, of which feline immunodeficiency virus was the most frequent. Dermatological lesions were frequently reported, and systemic clinical signs and clinicopathological abnormalities were also common. Serology may be useful for the diagnosis of FeL in clinical practice, and a positive titer of ≥ 1/40 may be a useful cut-off for sick cats. The reported treatments and dosages varied, but there was a good clinical response and longer survival in most of the cats treated with allopurinol monotherapy.
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Registered trials
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