Evidence map›Paper›PMID 35817878›Full record

ArticleJournal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry2022

Induction of apoptosis in SGC-7901 cells by iridium(III) complexes via endoplasmic reticulum stress-mitochondrial dysfunction pathway.

Jiawen Wang, Haimei Liu, Xiaoyun Wu, Chuanling Shi, Wenlong Li, Yuhan Yuan, Yunjun Liu, Degang Xing

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Synthesis, characterization, anticancer efficacy evaluation of ruthenium(II) and iridium(III) polypyridyl complexes toward A549 cells.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Jiawen WangSchool of Biosciences and Biopharmaceutics, Guangdong Pharmaceutical University, Guangzhou, 510006, People's Republic of China.
Haimei LiuSchool of Pharmacy, Guangdong Pharmaceutical University, Guangzhou, 510006, People's Republic of China.
Xiaoyun WuSchool of Pharmacy, Guangdong Pharmaceutical University, Guangzhou, 510006, People's Republic of China.
Chuanling ShiSchool of Pharmacy, Guangdong Pharmaceutical University, Guangzhou, 510006, People's Republic of China.
Wenlong LiSchool of Pharmacy, Guangdong Pharmaceutical University, Guangzhou, 510006, People's Republic of China.
Yuhan YuanSchool of Pharmacy, Guangdong Pharmaceutical University, Guangzhou, 510006, People's Republic of China.
Yunjun LiuSchool of Pharmacy, Guangdong Pharmaceutical University, Guangzhou, 510006, People's Republic of China. lyjche@gdpu.edu.cn.
Degang XingSchool of Biosciences and Biopharmaceutics, Guangdong Pharmaceutical University, Guangzhou, 510006, People's Republic of China. degangxing@126.com.
Guangdong Pharmaceutical University · CN

Funding

National Natural Science Foundation of China 21877018
6 · The paper itself

Abstract

This study was intended to evaluate the anticancer activity of three newly synthesized iridium(III) complexes [Ir(ppy)

Indexed as

Antineoplastic AgentsCoordination ComplexesAnimalsApoptosisBromidesCell Line, TumorCell ProliferationEndoplasmic Reticulum StressHumansIridiumMiceMitochondriaNIH 3T3 CellsPhenanthrolinesReactive Oxygen SpeciesAntineoplastic AgentsBromidesCoordination ComplexesIridiumPhenanthrolinesReactive Oxygen SpeciesApoptosis, Endoplasmic reticulumCytotoxicityIridium(III) complexesMitochondria

Identifiers

PMID35817878
OpenAlexW4285043869

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.