Evidence map›Paper›PMID 35817844›Full record

ReviewNature immunology2022

Targeting T

Di Yu, Lucy S K Walker, Zheng Liu, Michelle A Linterman, Zhanguo Li

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed, 1 pooled it
11.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed, 1 synthesis or guideline pooled it, 129 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Targeting T follicular helper cells for lifelong health.Nature reviews. Drug discovery · 2026
    Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Multimodal analysis definesbioRxiv : the preprint server for biology · 2025
    Article
  15. Article
  16. Article
  17. T follicular helper cells in primary immune regulatory disorders.The Journal of allergy and clinical immunology · 2025
    Review
  18. Article
  19. Article
  20. Article

5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 3 countries.

Di YuThe University of Queensland Diamantina Institute, Faculty of Medicine, The University of Queensland, Brisbane, Australia. di.yu@uq.edu.au.ORCID 0000-0003-1721-8922
Lucy S K WalkerInstitute of Immunity & Transplantation, Division of Infection & Immunity, University College London, Royal Free Campus, London, UK.ORCID 0000-0001-5986-5015
Zheng LiuDepartment of Otolaryngology-Head and Neck Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.ORCID 0000-0002-4168-6702
Michelle A LintermanImmunology Programme, Babraham Institute, Cambridge, UK.ORCID 0000-0001-6047-1996
Zhanguo LiDepartment of Rheumatology & Immunology, Peking University People's Hospital, Beijing, China.
Babraham Institute · GBChildren's Medical Research Institute · AUPeking University · CNThe Royal Free Hospital · GBTongji Hospital · CN

Funding

Biotechnology and Biological Sciences Research Council BBS/E/B/000C0407Biotechnology and Biological Sciences Research Council BBS/E/B/000C0427Medical Research Council MR/N001435/1Wellcome Trust 220772/Z/20/Z
6 · The paper itself

Abstract

The identification of CD4

Indexed as

Germinal CenterT-Lymphocytes, Helper-InducerAntibody FormationB-LymphocytesCell DifferentiationHumansVaccination

Identifiers

PMID35817844
OpenAlexW4285011745

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.