ArticleNature ecology & evolution2022
Comparative genome anatomy reveals evolutionary insights into a unique amphitriploid fish.
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Article in Nature ecology & evolution, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
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40 citing papers in PubMed, 71 citations in OpenAlex.
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- Evolutionary diversification and immunoprofiling of cathepsin L toolkit in common carp.Frontiers in cellular and infection microbiology · 2026Article
- amh alleles on XY sex chromosomes regulate male differentiation in amphidiploid Carassius auratus.Science China. Life sciences · 2026Article
- Triploidy drives vector capacity and expansion of the parthenogenetic tick Haemaphysalis longicornis.Communications biology · 2025Article
- The Influence of Genome Composition and Temperature on the Hatching Success and Development of the Offspring of AllotriploidInternational journal of molecular sciences · 2025Article
- Subgenome Partitioning and Polyploid Genome Evolution in the Loach Family Botiidae (Order Cypriniformes).Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Manipulating Unisexual-Sexual Reproduction Transition to Engineer Genome-Reconstructed Polyploids.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Chromosome-level genome assembly of Qihe gibel carp.Scientific data · 2025Article
- Expression pattern changes of three homeologs in chemokine activity enhance antiviral response to herpesvirus infection in a newly synthesized alloheptaploid.BMC genomics · 2025Article
- Chromosome-level de novo genome assembly of wild, anoxia-tolerant crucian carp, Carassius carassius.Scientific data · 2025Article
- A chromosome-level genome assembly of the mud carp (Cirrhinus molitorella).Scientific data · 2025Article
- The Observation of Meiotic Union Behavior of Gametophytes Provides a New Basis for Ploidy ofAnimals : an open access journal from MDPI · 2025Article
- Telomere-to-telomere genome assembly of Electrophorus electricus provides insights into the evolution of electric eels.GigaScience · 2025Article
- Arachidonic Acid Metabolism Down-Regulation-Mediated Tumor Necrosis Factor Signaling Contributes to Cutaneous Fibrosis and Skull Hyperplasia in Goldfish Hoods.Research (Washington, D.C.) · 2025Article
- Morpho-histological and Transcriptome Analysis Reveal the Unreduced Sperm Formation Mechanism in cdk1-Depletion Zebrafish.Marine biotechnology (New York, N.Y.) · 2024Article
- An improved transcriptome annotation reveals asymmetric expression and distinct regulation patterns in allotetraploid common carp.Communications biology · 2024Article
- Decoding the fish genome opens a new era in important trait research and molecular breeding in China.Science China. Life sciences · 2024Review
- Evolution of Key Oxygen-Sensing Genes Is Associated with Hypoxia Tolerance in Fishes.Genome biology and evolution · 2024Article
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Authors and funding
45 authors at 4 institutions in 2 countries.
Yang Wang *State Key Laboratory of Freshwater Ecology and Biotechnology, Hubei Hongshan Laboratory, The Innovation Academy of Seed Design, University of Chinese Academy of Sciences, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.ORCID http://orcid.org/0000-0003-0727-607X
Xi-Yin Li *State Key Laboratory of Freshwater Ecology and Biotechnology, Hubei Hongshan Laboratory, The Innovation Academy of Seed Design, University of Chinese Academy of Sciences, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.ORCID http://orcid.org/0000-0002-6639-0481
Wen-Jie Xu *School of Ecology and Environment, Northwestern Polytechnical University, Xi'an, China.
Kun Wang *School of Ecology and Environment, Northwestern Polytechnical University, Xi'an, China.ORCID http://orcid.org/0000-0001-6059-6529
Bin Wu *BGI Genomics, BGI-Shenzhen, Shenzhen, China.
Meng Xu *BGI Genomics, BGI-Shenzhen, Shenzhen, China.ORCID http://orcid.org/0000-0003-4747-7319
Yan Chen *State Key Laboratory of Freshwater Ecology and Biotechnology, Hubei Hongshan Laboratory, The Innovation Academy of Seed Design, University of Chinese Academy of Sciences, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.ORCID http://orcid.org/0000-0002-9806-6782
Li-Jun MiaoState Key Laboratory of Freshwater Ecology and Biotechnology, Hubei Hongshan Laboratory, The Innovation Academy of Seed Design, University of Chinese Academy of Sciences, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.ORCID http://orcid.org/0000-0002-1372-840X
Zhong-Wei WangState Key Laboratory of Freshwater Ecology and Biotechnology, Hubei Hongshan Laboratory, The Innovation Academy of Seed Design, University of Chinese Academy of Sciences, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.
Zhi LiState Key Laboratory of Freshwater Ecology and Biotechnology, Hubei Hongshan Laboratory, The Innovation Academy of Seed Design, University of Chinese Academy of Sciences, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.
Xiao-Juan ZhangState Key Laboratory of Freshwater Ecology and Biotechnology, Hubei Hongshan Laboratory, The Innovation Academy of Seed Design, University of Chinese Academy of Sciences, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.ORCID http://orcid.org/0000-0002-2679-5775
Zhan YinState Key Laboratory of Freshwater Ecology and Biotechnology, Hubei Hongshan Laboratory, The Innovation Academy of Seed Design, University of Chinese Academy of Sciences, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.
Bo-Tong ZhouSchool of Ecology and Environment, Northwestern Polytechnical University, Xi'an, China.ORCID http://orcid.org/0000-0002-1091-5867
Yu-Lan YangBGI Genomics, BGI-Shenzhen, Shenzhen, China.
Cheng-Long ZhuSchool of Ecology and Environment, Northwestern Polytechnical University, Xi'an, China.
Ming-Liang HuSchool of Ecology and Environment, Northwestern Polytechnical University, Xi'an, China.ORCID http://orcid.org/0000-0001-9018-6715
Jiang-Ming ZhengSchool of Ecology and Environment, Northwestern Polytechnical University, Xi'an, China.
Chen-Guang FengSchool of Ecology and Environment, Northwestern Polytechnical University, Xi'an, China.ORCID http://orcid.org/0000-0002-4566-6848
Qiang QiuSchool of Ecology and Environment, Northwestern Polytechnical University, Xi'an, China.
Le-Tian TianState Key Laboratory of Freshwater Ecology and Biotechnology, Hubei Hongshan Laboratory, The Innovation Academy of Seed Design, University of Chinese Academy of Sciences, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.
Meng LuState Key Laboratory of Freshwater Ecology and Biotechnology, Hubei Hongshan Laboratory, The Innovation Academy of Seed Design, University of Chinese Academy of Sciences, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.ORCID http://orcid.org/0000-0002-7030-9623
Fang PengState Key Laboratory of Freshwater Ecology and Biotechnology, Hubei Hongshan Laboratory, The Innovation Academy of Seed Design, University of Chinese Academy of Sciences, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.ORCID http://orcid.org/0000-0001-6286-3459
Wei-Jia LuState Key Laboratory of Freshwater Ecology and Biotechnology, Hubei Hongshan Laboratory, The Innovation Academy of Seed Design, University of Chinese Academy of Sciences, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.
Jin-Feng TongState Key Laboratory of Freshwater Ecology and Biotechnology, Hubei Hongshan Laboratory, The Innovation Academy of Seed Design, University of Chinese Academy of Sciences, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.
Jin-Gou TongState Key Laboratory of Freshwater Ecology and Biotechnology, Hubei Hongshan Laboratory, The Innovation Academy of Seed Design, University of Chinese Academy of Sciences, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.ORCID http://orcid.org/0000-0001-7384-1239
Bei-De FuState Key Laboratory of Freshwater Ecology and Biotechnology, Hubei Hongshan Laboratory, The Innovation Academy of Seed Design, University of Chinese Academy of Sciences, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.ORCID http://orcid.org/0000-0002-0264-5262
Peng YuState Key Laboratory of Freshwater Ecology and Biotechnology, Hubei Hongshan Laboratory, The Innovation Academy of Seed Design, University of Chinese Academy of Sciences, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.ORCID http://orcid.org/0000-0002-8754-1736
Miao DingState Key Laboratory of Freshwater Ecology and Biotechnology, Hubei Hongshan Laboratory, The Innovation Academy of Seed Design, University of Chinese Academy of Sciences, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.ORCID http://orcid.org/0000-0001-6420-4094
Rui-Hai GanState Key Laboratory of Freshwater Ecology and Biotechnology, Hubei Hongshan Laboratory, The Innovation Academy of Seed Design, University of Chinese Academy of Sciences, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.ORCID http://orcid.org/0000-0002-5565-9131
Qin-Qin ZhangState Key Laboratory of Freshwater Ecology and Biotechnology, Hubei Hongshan Laboratory, The Innovation Academy of Seed Design, University of Chinese Academy of Sciences, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.
Jian-Bo JianBGI Genomics, BGI-Shenzhen, Shenzhen, China.
Chi ZhangBGI Genomics, BGI-Shenzhen, Shenzhen, China.
Wei-Ming HeBGI Genomics, BGI-Shenzhen, Shenzhen, China.
Wei YangBGI Genomics, BGI-Shenzhen, Shenzhen, China.
Zi-Cheng ZhaoBGI Genomics, BGI-Shenzhen, Shenzhen, China.
Qian-Qian ZhangBGI Genomics, BGI-Shenzhen, Shenzhen, China.
Qiang GaoBGI Genomics, BGI-Shenzhen, Shenzhen, China.
Jun-Yang XuBGI Genomics, BGI-Shenzhen, Shenzhen, China.
Ming-Zhou BaiBGI Genomics, BGI-Shenzhen, Shenzhen, China.
Ya-Ping ZhangState Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China.ORCID http://orcid.org/0000-0002-5401-1114
Huan-Ming YangBGI Genomics, BGI-Shenzhen, Shenzhen, China.
Xiao-Dong FangBGI Genomics, BGI-Shenzhen, Shenzhen, China. fangxd@bgi.com.ORCID http://orcid.org/0000-0001-7061-3337
Wen WangSchool of Ecology and Environment, Northwestern Polytechnical University, Xi'an, China. wenwang@nwpu.edu.cn.ORCID http://orcid.org/0000-0002-7801-2066
Li ZhouState Key Laboratory of Freshwater Ecology and Biotechnology, Hubei Hongshan Laboratory, The Innovation Academy of Seed Design, University of Chinese Academy of Sciences, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China. zhouli@ihb.ac.cn.ORCID http://orcid.org/0000-0002-3511-3449
Jian-Fang GuiState Key Laboratory of Freshwater Ecology and Biotechnology, Hubei Hongshan Laboratory, The Innovation Academy of Seed Design, University of Chinese Academy of Sciences, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China. jfgui@ihb.ac.cn.ORCID http://orcid.org/0000-0003-4969-1482
Institute of Hydrobiology · CNBGI Group (China) · CNNorthwestern Polytechnical University · CNKunming Institute of Zoology · CN
Funding
No grant is acknowledged in the PubMed record.
Abstract
Triploids are rare in nature because of difficulties in meiotic and gametogenic processes, especially in vertebrates. The Carassius complex of cyprinid teleosts contains sexual tetraploid crucian carp/goldfish (C. auratus) and unisexual hexaploid gibel carp/Prussian carp (C. gibelio) lineages, providing a valuable model for studying the evolution and maintenance mechanism of unisexual polyploids in vertebrates. Here we sequence the genomes of the two species and assemble their haplotypes, which contain two subgenomes (A and B), to the chromosome level. Sequencing coverage analysis reveals that C. gibelio is an amphitriploid (AAABBB) with two triploid sets of chromosomes; each set is derived from a different ancestor. Resequencing data from different strains of C. gibelio show that unisexual reproduction has been maintained for over 0.82 million years. Comparative genomics show intensive expansion and alterations of meiotic cell cycle-related genes and an oocyte-specific histone variant. Cytological assays indicate that C. gibelio produces unreduced oocytes by an alternative ameiotic pathway; however, sporadic homologous recombination and a high rate of gene conversion also exist in C. gibelio. These genomic changes might have facilitated purging deleterious mutations and maintaining genome stability in this unisexual amphitriploid fish. Overall, the current results provide novel insights into the evolutionary mechanisms of the reproductive success in unisexual polyploid vertebrates.
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CarpsPolyploidyAnimalsGenomeGoldfishReproduction
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