Evidence map›Paper›PMID 35817818›Full record

ArticleScientific reports2022

The COVID-19 pandemic in Brazilian pregnant and postpartum women: results from the REBRACO prospective cohort study.

Renato T Souza, Jose G Cecatti, Rodolfo C Pacagnella, Carolina C Ribeiro-Do-Valle, Adriana G Luz, Giuliane J Lajos, Guilherme M Nobrega, Thayna B Griggio, Charles M Charles, Silvana F Bento and 22 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Article
  6. Article
  7. Five years after the COVID-19 pandemic began: lessons on vaccination and obstetric care in Brazil.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2025
    Article
  8. Article
  9. Severe COVID-19 in pregnancy: evaluation of ventilatory outcomes on a 101-cases cohort.Revista do Instituto de Medicina Tropical de Sao Paulo · 2025
    Article
  10. Observational
  11. Brazilian Black Women are at Higher Risk for COVID-19 Complications: An Analysis of REBRACO, a National Cohort.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2023
    Article
  12. Review
  13. COVID-19 in pregnancy: evidence from LMICs.The Lancet. Global health · 2022
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

32 authors at 15 institutions in 1 country.

Renato T SouzaDepartment of Obstetrics and Gynecology, University of Campinas, 101 Alexander Fleming St, Campinas, SP, Brazil.
Jose G CecattiDepartment of Obstetrics and Gynecology, University of Campinas, 101 Alexander Fleming St, Campinas, SP, Brazil.
Rodolfo C PacagnellaDepartment of Obstetrics and Gynecology, University of Campinas, 101 Alexander Fleming St, Campinas, SP, Brazil.
Carolina C Ribeiro-Do-ValleDepartment of Obstetrics and Gynecology, University of Campinas, 101 Alexander Fleming St, Campinas, SP, Brazil.
Adriana G LuzDepartment of Obstetrics and Gynecology, University of Campinas, 101 Alexander Fleming St, Campinas, SP, Brazil.
Giuliane J LajosDepartment of Obstetrics and Gynecology, University of Campinas, 101 Alexander Fleming St, Campinas, SP, Brazil.
Guilherme M NobregaDepartment of Obstetrics and Gynecology, University of Campinas, 101 Alexander Fleming St, Campinas, SP, Brazil.
Thayna B GriggioDepartment of Obstetrics and Gynecology, University of Campinas, 101 Alexander Fleming St, Campinas, SP, Brazil.
Charles M CharlesDepartment of Obstetrics and Gynecology, University of Campinas, 101 Alexander Fleming St, Campinas, SP, Brazil.
Silvana F BentoDepartment of Obstetrics and Gynecology, University of Campinas, 101 Alexander Fleming St, Campinas, SP, Brazil.
Carla SilveiraDepartment of Obstetrics and Gynecology, University of Campinas, 101 Alexander Fleming St, Campinas, SP, Brazil.
Fernanda G SuritaDepartment of Obstetrics and Gynecology, University of Campinas, 101 Alexander Fleming St, Campinas, SP, Brazil.
Maria J MieleDepartment of Obstetrics and Gynecology, University of Campinas, 101 Alexander Fleming St, Campinas, SP, Brazil.
Ricardo P TedescoJundiaí School of Medicine-HU/FMJ, Jundiaí, SP, Brazil.
Karayna G FernandesJundiaí School of Medicine-HU/FMJ, Jundiaí, SP, Brazil.
Sérgio H A Martins-CostaClinics Hospital of Porto Alegre, Porto Alegre, RS, Brazil.
Frederico J A PeretUNIMED Maternity-UNIMED/BH, Belo Horizonte, MG, Brazil.
Francisco E FeitosaFederal University of Ceará-MEAC/UFC, Fortaleza, CE, Brazil.
Rosiane MattarFederal University of São Paulo-UNIFESP/EPM, São Paulo, SP, Brazil.
Evelyn TrainaFederal University of São Paulo-UNIFESP/EPM, São Paulo, SP, Brazil.
Edson V Cunha FilhoMoinhos de Vento Hospital-HMV, Porto Alegre, RS, Brazil.
Janete VettorazziClinics Hospital of Porto Alegre, Porto Alegre, RS, Brazil.
Samira M HaddadJorge Rossmann Regional Hospital-Sócrates Guanaes Institute, Itanhaém, SP, Brazil.
Carla B AndreucciFederal University of São Carlos/UFSCAR, São Carlos, SP, Brazil.
José P GuidaSumaré State Hospital-HES, Sumaré, SP, Brazil.
Mario D Correa JuniorFederal University of Minas Gerais-HC/UFMG, Belo Horizonte, MG, Brazil.
Marcos A B DiasFernandes Figueira Institute-IFF/Fiocruz, Rio de Janeiro, RJ, Brazil.
Leandro De OliveiraSão Paulo State University School of Medicine, Botucatu, SP, Brazil.
Elias F Melo JuniorFederal University of Pernambuco-HC/UFPE, Recife, PE, Brazil.
Marília G Q LuzSanta Casa de Misericórdia of Pará, Belém, PA, Brazil.
Maria Laura CostaDepartment of Obstetrics and Gynecology, University of Campinas, 101 Alexander Fleming St, Campinas, SP, Brazil. mlaura@unicamp.br.
REBRACO Study Group
Universidade Estadual de Campinas (UNICAMP) · BRSanta Casa de Misericórdia de Marília · BRFaculdade de Medicina de Jundiaí · BRCentro Universitário de Belo Horizonte · BRHospital de Clínicas de Porto Alegre · BRHospital Moinhos de Vento · BRUniversidade Federal de São Paulo · BRUniversidade Federal do Ceará · BRUniversidade Estadual Paulista (Unesp) · BRUniversidade Federal de Minas Gerais · BRUniversidade Federal de Pernambuco · BRUniversidade Federal de São Carlos · BRFaculdade Sumaré · BRFundação Instituto de Pesca do Estado do Rio de Janeiro · BRHospital Infantil Joana de Gusmão · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Brazil presented a very high number of maternal deaths and evident delays in healthcare. We aimed at evaluating the characteristics of SARS-CoV-2 infection and associated outcomes in the obstetric population. We conducted a prospective cohort study in 15 Brazilian centers including symptomatic pregnant or postpartum women with suspected COVID-19 from Feb/2020 to Feb/2021. Women were followed from suspected infection until the end of pregnancy. We analyzed maternal characteristics and pregnancy outcomes associated with confirmed COVID-19 infection and SARS, determining unadjusted risk ratios. In total, 729 symptomatic women with suspected COVID-19 were initially included. Among those investigated for COVID-19, 51.3% (n = 289) were confirmed COVID-19 and 48% (n = 270) were negative. Initially (before May 15th), only 52.9% of the suspected cases were tested and it was the period with the highest proportion of ICU admission and maternal deaths. Non-white ethnicity (RR 1.78 [1.04-3.04]), primary schooling or less (RR 2.16 [1.21-3.87]), being overweight (RR 4.34 [1.04-19.01]) or obese (RR 6.55 [1.57-27.37]), having public prenatal care (RR 2.16 [1.01-4.68]), planned pregnancies (RR 2.09 [1.15-3.78]), onset of infection in postpartum period (RR 6.00 [1.37-26.26]), chronic hypertension (RR 2.15 [1.37-4.10]), pre-existing diabetes (RR 3.20 [1.37-7.46]), asthma (RR 2.22 [1.14-4.34]), and anaemia (RR 3.15 [1.14-8.71]) were associated with higher risk for SARS. The availability of tests and maternal outcomes varied throughout the pandemic period of the study; the beginning was the most challenging period, with worse outcomes. Socially vulnerable, postpartum and previously ill women were more likely to present SARS related to COVID-19.

Indexed as

COVID-19PandemicsPregnancy Complications, InfectiousBrazilFemaleHumansMaternal DeathPostpartum PeriodPregnancyProspective StudiesSARS-CoV-2

Identifiers

PMID35817818
PMCPMC9272878
OpenAlexW4285043034

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.