ArticleBJPsych open2022
Examining the common and specific grey matter abnormalities in childhood maltreatment and peer victimisation.
Article in BJPsych open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 14 citations in OpenAlex.
- Persistent structural alteration of the extended limbic system in adolescents with childhood maltreatment.European psychiatry : the journal of the Association of European Psychiatrists · 2026Article
- Atypical Neural Activation During Emotional but Not Nonemotional Response Inhibition in Healthy Young People Exposed to Childhood Maltreatment and Peer Victimization.Biological psychiatry global open science · 2025Article
- Editorial on Child Abuse and Neglect II.Children (Basel, Switzerland) · 2025Article
- Workplace Violence Is Home Now for Healthcare Workers: Spillover Theory Perspective.Stress and health : journal of the International Society for the Investigation of Stress · 2025Article
- Effects of childhood trauma on sustained attention in major depressive disorder: the mediating role of brain activity and functional connectivity.BMC psychiatry · 2024Article
- Atypical brain structural connectivity and social cognition in childhood maltreatment and peer victimisation.BMC psychiatry · 2024Article
- Cingulate cortical thickness in cocaine use disorder: mediation effect between early life stress and cocaine consumption.Acta neuropsychiatrica · 2024Article
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Authors and funding
2 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEarly-life interpersonal stress, particularly childhood maltreatment, is associated with neurobiological abnormalities. However, few studies have investigated the neural effects of peer victimisation.
aimsThis study examines common and specific associations between childhood maltreatment, peer victimisation and brain structural alterations in youths.
methodGrey matter volume (GMV) and cortical thickness data were collected from 105 age- and gender-matched youths (age range: 17-21 years). Region-of-interest and whole-brain analyses were conducted.
resultsFor the region-of-interest analyses, the childhood maltreatment group had smaller GMV than controls in left inferior frontal gyrus, bilateral anterior insula, postcentral and lingual regions, which were associated with greater emotional abuse, along with smaller insular GMV than the peer victimisation group, who had smaller left lingual and postcentral GMV than controls. At the whole-brain level, both childhood maltreatment and peer victimisation groups had smaller GMV than controls in a cluster comprising left post/precentral, inferior frontal gyrus, insula, superior parietal and supramarginal gyri. The peer victimisation group alone had increased cortical thickness in a cluster comprising left superior frontal, anterior cingulate and medial orbitofrontal gyri, which was related to greater cyberbullying.
conclusionsEarly-life interpersonal stress is associated with common structural alterations of the inferior frontal-limbic, sensory and lingual regions involved in cognitive control, emotion and sensory processing. The findings of childhood-maltreatment-related reduced anterior insular GMV and peer-victimisation-related increased cortical thickness in the left medial prefrontal-anterior cingulate cluster underscore the distinctive negative effects of childhood maltreatment and peer victimisation, and suggest that peer victimisation, particularly cyberbullying, could be as detrimental as childhood maltreatment.
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