Evidence map›Paper›PMID 35817652›Full record

ReviewTrends in biochemical sciences2022

Intrinsic and extrinsic regulators of Aux/IAA protein degradation dynamics.

Marcelo Rodrigues Alves de Figueiredo, Lucia C Strader

Open access · greenAbstract readReview
In one paragraph

Review in Trends in biochemical sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
10.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 50 citations in OpenAlex.

  1. Article
  2. Mechanisms of auxin action in plant growth and development.Nature reviews. Molecular cell biology · 2025
    Review
  3. Article
  4. Article
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  7. Article
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  11. Article
  12. Article
  13. Review
  14. Article
  15. Genome-Wide Identification and Analysis of the Aux/IAA Gene Family inInternational journal of molecular sciences · 2024
    Article
  16. Genome-Wide Identification of theInternational journal of molecular sciences · 2024
    Article
  17. Article
  18. Article
  19. Plant signaling & behavior · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Marcelo Rodrigues Alves de FigueiredoDepartment of Biology, Duke University, Durham, NC, USA.
Lucia C StraderDepartment of Biology, Duke University, Durham, NC, USA. Electronic address: lucia.strader@duke.edu.
Duke University · US

Funding

NIGMS administrative equipment supplement for R35 GM136338-02R35GM136338 · NIGMS · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI Lucia Strader · 2020 to 2026
$3.2M
NIGMS NIH HHS R35 GM136338
6 · The paper itself

Abstract

The plant hormone auxin acts through regulated degradation of Auxin/INDOLE-3-ACETIC ACID (Aux/IAA) proteins to regulate transcriptional events. In this review, we examine the composition and function of each Aux/IAA structural motif. We then focus on recent characterization of Aux/IAA N-terminal disordered regions, formation of secondary structure within these disordered regions, and post-translational modifications (PTMs) that affect Aux/IAA function and stability. We propose how structural variations between Aux/IAA family members may be tuned for differential transcriptional repression and degradation dynamics.

Indexed as

Arabidopsis ProteinsIndoleacetic AcidsNuclear ProteinsPlant Growth RegulatorsProteolysisArabidopsis ProteinsIndoleacetic AcidsNuclear ProteinsPlant Growth Regulatorsauxinbinding contextdegronintrinsically disorder regionsSLiM

Identifiers

PMID35817652
PMCPMC9464691
OpenAlexW4284966749

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.