Evidence map›Paper›PMID 35817564›Full record

ArticleClinical endoscopy2022

Bispectral index-guided propofol sedation during endoscopic ultrasonography.

Ayana Okamoto, Ken Kamata, Takeshi Miyata, Tomoe Yoshikawa, Rei Ishikawa, Tomohiro Yamazaki, Atsushi Nakai, Shunsuke Omoto, Kosuke Minaga, Kentaro Yamao and 6 more

Open access · goldAbstract read
In one paragraph

Article in Clinical endoscopy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 1 country.

Ayana OkamotoDepartment of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Osakasayama, Japan.
Ken KamataDepartment of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Osakasayama, Japan.
Takeshi MiyataDepartment of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Osakasayama, Japan.
Tomoe YoshikawaDepartment of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Osakasayama, Japan.
Rei IshikawaDepartment of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Osakasayama, Japan.
Tomohiro YamazakiDepartment of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Osakasayama, Japan.
Atsushi NakaiDepartment of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Osakasayama, Japan.
Shunsuke OmotoDepartment of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Osakasayama, Japan.
Kosuke MinagaDepartment of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Osakasayama, Japan.
Kentaro YamaoDepartment of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Osakasayama, Japan.
Mamoru TakenakaDepartment of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Osakasayama, Japan.
Yasutaka ChibaClinical Research Center, Kindai University Hospital, Osakasayama, Japan.
Toshiharu SakuraiDepartment of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Osakasayama, Japan.
Naoshi NishidaDepartment of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Osakasayama, Japan.
Masayuki KitanoSecond Department of Internal Medicine, Wakayama Medical University School of Medicine, Wakayama, Japan.
Masatoshi KudoDepartment of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Osakasayama, Japan.
Kindai University · JPKindai University Hospital · JPWakayama Medical University · JP

Funding

Japan Research Foundation for Clinical Pharmacology
6 · The paper itself

Abstract

BACKGROUND/

aimsBispectral index (BIS) monitors process and display electroencephalographic data are used to assess the depth of anesthesia. This study retrospectively evaluated the usefulness of BIS monitoring during endoscopic ultrasonography (EUS).

methodsThis study included 725 consecutive patients who underwent EUS under sedation with propofol. BIS monitoring was used in 364 patients and was not used in 361. The following parameters were evaluated: (1) median dose of propofol; (2) respiratory and circulatory depression; (3) occurrence of body movements; (4) awakening score >8 at the time; and (5) awakening score 2 hours after leaving the endoscopy room.

resultsThe BIS group received a significantly lower median dose of propofol than the non-BIS group (159.2 mg vs. 167.5 mg; p=0.015) in all age groups. For patients aged ≥75 years, the reduction in heart rate was significantly lower in the BIS group than in the non-BIS group (1.2% vs. 9.1%; p=0.023). Moreover, the occurrence of body movements was markedly lower in the BIS group than in the non-BIS group (8.5% vs. 39.4%; p<0.001).

conclusionDuring EUS examination, BIS monitoring is useful for maintaining a constant depth of anesthesia, especially in patients 75 years of age or older.

Indexed as

Consciousness monitorsEndosonographyIntravenous anesthesiaMidazolamPropofol

Identifiers

PMID35817564
PMCPMC9329640
OpenAlexW4285026588

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.