Evidence map›Paper›PMID 35817494›Full record

ArticleBMJ case reports2022

Limbic system symptoms of rabies infection.

Ritin Mohindra, Mohata Madhav, Vikas Suri, Krishna Divyashree

Abstract readCase Reports
In one paragraph

Article in BMJ case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ritin MohindraInternal Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Mohata MadhavInternal Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Vikas SuriInternal Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Krishna DivyashreeInternal Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh, India divyashreek95@gmail.com.ORCID http://orcid.org/0000-0001-8333-9445

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rabies is a fatal aggressive disease of the nervous system which predominantly causes motor and autonomic dysfunction. Limbic system involvement has been reported rarely, with limited data on its prevalence. The diagnosis becomes challenging when a patient presents with limbic system involvement in the absence of a clear history of an animal bite. We herein illustrate a case of a young man who presented with recurrent episodes of inappropriate ejaculation. He eventually developed hydrophobia and aerophobia, leading to a diagnosis of rabies. This case emphasises the importance of considering the possibility of rabies encephalitis when a patient presents with symptoms of limbic system involvement since early diagnosis helps in instituting appropriate public health measures and reducing exposure to infection. Furthermore, high-quality intensive care with supportive management is the mainstay of therapy in such patients until we have novel and effective antiviral drugs for rabies treatment.

Indexed as

Bites and StingsRabiesRabies VaccinesRabies virusAnimalsHumansLimbic SystemMalePhobic DisordersRabies VaccinesInfection control in hospitalInfection (neurology)Vaccination/immunisation

Identifiers

PMID35817494
PMCPMC9274529

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.